Title:
DEVICE AND PROCESS FOR REMOVING LEUKOCYTES AND VIRAL INACTIVATING AGENTS FROM BLOOD
Document Type and Number:
WIPO Patent Application WO/1995/018665
Kind Code:
A1
Abstract:
Filters (hollow-fibers, flat-sheet membranes or depth filters) for removing leukocytes and viral inactivating agents from whole blood or blood fractions are disclosed. One type of depth filter comprises a laid textile web which has been modified to attach a ligand for viral inactivating agents, a ligand for leukocytes, or ligands for both. An exemplary membrane comprises a polyethersulfone membrane that has been similarly modified. Filter devices for simultaneously removing leukocytes and viral inactivating agents from whole blood or blood fractions are also disclosed. One type of device comprises (1) a housing surrounding (2) activated carbon and (3) a mechanically stable polymeric material which may optionally be modified to attach a ligand for leukocytes. General methods for removing leukocytes and rival inactivating agents from blood are also disclosed.
Inventors:
CASTINO FRANCO
AZAD ABDUL R M
LEE ERIC KIN-LAM
FOURON YVES
ZEPP CHARLES M
AZAD ABDUL R M
LEE ERIC KIN-LAM
FOURON YVES
ZEPP CHARLES M
Application Number:
PCT/US1995/000355
Publication Date:
July 13, 1995
Filing Date:
January 10, 1995
Export Citation:
Assignee:
HEMASURE INC (US)
International Classes:
A61M1/36; B01D37/00; B01D39/02; B01D39/04; B01D39/16; B01D67/00; B01J20/26; (IPC1-7): B01D39/16; B01D67/00
Domestic Patent References:
| WO1990005018A1 | 1990-05-17 | |||
| WO1991003933A1 | 1991-04-04 | |||
| WO1993016176A1 | 1993-08-19 |
Foreign References:
| EP0173500A1 | 1986-03-05 | |||
| US5190657A | 1993-03-02 | |||
| EP0341413A2 | 1989-11-15 |
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