Title:
DEVICE FOR THE TRANSDERMAL DELIVERY OF DICLOFENAC
Document Type and Number:
WIPO Patent Application WO1999051212
Kind Code:
A3
Abstract:
The present invention provides a pressure sensitive skin adhesive comprising: (a) a copolymer of one or more alkyl(meth)acrylates containing 4 to 12 carbon atoms in the alkyl group and one or more hydrophilic monomers; (b) a mixture of penetration enhancers comprising: (i) an alkyl ester of an aliphatic monocarboxylic acid containing 1 to 5 carbon atoms in the alkyl group; (ii) an alkyl pyrrolidone and (iii) an alkane polyol; (c) a therapeutically effective amount of diclofenac or a pharmaceutically acceptable salt thereof. Further provided is a transdermal drug delivery device containing the pressure sensitive skin adhesive.
Inventors:
EFFING JOCHEM J
BECKER ANJA N
COORS CARSTEN
BECKER ANJA N
COORS CARSTEN
Application Number:
PCT/US1999/006779
Publication Date:
December 02, 1999
Filing Date:
March 29, 1999
Export Citation:
Assignee:
MINNESOTA MINING & MFG (US)
International Classes:
A61K9/70; A61K31/196; A61K47/22; A61K47/34; A61P29/00; A61P31/04; A61K47/10; A61K47/14; (IPC1-7): A61K9/70; A61K47/00; A61K31/195; A61K47/32
Foreign References:
| EP0582727A1 | 1994-02-16 | |||
| EP0452837A2 | 1991-10-23 | |||
| US5505956A | 1996-04-09 |
Other References:
DATABASE WPI Week 9544, Derwent World Patents Index; AN 1995-340179 [44], XP002117705
DATABASE WPI Week 9038, Derwent World Patents Index; AN 1990-287110 [25], XP002117706
CHEMICAL ABSTRACTS, vol. 127, no. 6, 11 August 1997, Columbus, Ohio, US; abstract no. 86111, XP002117703
CHEMICAL ABSTRACTS, vol. 102, no. 18, 6 May 1985, Columbus, Ohio, US; abstract no. 154817, XP002117704
DATABASE WPI Week 9038, Derwent World Patents Index; AN 1990-287110 [25], XP002117706
CHEMICAL ABSTRACTS, vol. 127, no. 6, 11 August 1997, Columbus, Ohio, US; abstract no. 86111, XP002117703
CHEMICAL ABSTRACTS, vol. 102, no. 18, 6 May 1985, Columbus, Ohio, US; abstract no. 154817, XP002117704
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