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Title:
DEVICES AND METHODS FOR DETECTING NOROVIRUS ON SURFACES
Document Type and Number:
WIPO Patent Application WO/2016/082162
Kind Code:
A1
Abstract:
Lateral-flow assay and time-resolved fluorescence technologies provide a sensitive tool for detecting norovirus particles in a sample. A flow-through assay device employs norovirus and norovirus G2 antibodies. The lateral-flow assay includes a conjugate pad having conjugated probes. The conjugated probes are particles modified with a binding member that is configured to bind with a norovirus. The particles also have a fluorescent label. A general method of detecting the virus includes (i) preparing a sample with contaminants, (ii) processing the sample and depositing it onto the assay device, and (iii) measuring the fluorescence signal.

Inventors:
HE AIMIN (US)
HOFMEKLER JONATHAN (US)
KOENIG DAVID WILLIAM (US)
MORALES CESAR A (US)
DO BAO TRONG (US)
HUANG YANG (CN)
Application Number:
PCT/CN2014/092404
Publication Date:
June 02, 2016
Filing Date:
November 27, 2014
Export Citation:
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Assignee:
KIMBERLY CLARK CO (US)
HE AIMIN (US)
International Classes:
C12Q1/70; G01N33/569; G01N33/577; G01N33/58; C12R1/93
Foreign References:
CN1675545A2005-09-28
CN203759021U2014-08-06
Other References:
GUO LI ET AL.: "Preparation and characterization of monoclonal antibodies against Norovirus capsid protein", CHINESE JOURNAL OF ZOONOSES, vol. 22, no. 5, 31 December 2006 (2006-12-31), pages 414 - 418, ISSN: 1002-2694
Attorney, Agent or Firm:
PANAWELL & PARTNERS, LLC (China Life Tower16 Chao Yang Men Wai Street, Chaoyang District, Beijing 0, CN)
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