Title:
DIAGNOSTIC IMAGING AGENT FOR EARLY BONE METASTASIS FROM CANCER
Document Type and Number:
WIPO Patent Application WO/2016/194372
Kind Code:
A1
Abstract:
There is provided a diagnostic imaging agent for early bone metastasis from cancer, containing trans-1-amino-[18F]fluorocyclobutanecarboxylic acid or a pharmaceutically acceptable salt thereof as an active ingredient.
Inventors:
OKA SHUNTARO (JP)
KANAGAWA MASARU (JP)
OTAKA AKIHARU (JP)
TERAMACHI MASAKO (JP)
WATANABE SATOSHI (JP)
NAGATOMO TOSHIE (JP)
KANAGAWA MASARU (JP)
OTAKA AKIHARU (JP)
TERAMACHI MASAKO (JP)
WATANABE SATOSHI (JP)
NAGATOMO TOSHIE (JP)
Application Number:
PCT/JP2016/002654
Publication Date:
December 08, 2016
Filing Date:
June 01, 2016
Export Citation:
Assignee:
NIHON MEDIPHYSICS CO LTD (JP)
International Classes:
A61K51/00
Domestic Patent References:
| WO2007016285A2 | 2007-02-08 |
Foreign References:
| US20020131934A1 | 2002-09-19 | |||
| US7632486B1 | 2009-12-15 |
Other References:
SCHUSTER, D.M. ET AL.: "Anti-3-[18F] FACBC positron emission tomography-computerized tomography and IIIIn-capromab pendetide single photon emission computerized tomography-computerized tomography for recurrent prostate carcinoma: Results of a prospective clinical trial", JOURNAL OF UROLOGY, vol. 191, no. 5, 2014, pages 1446 - 1453, XP055332955
SHUSTER, D. ET AL.: "Report of a clinical trial of anti-1 amino 3 [18F]fluorocyclobutane-1- carboxylic acid (anti-[18F]FACBC) PET-CT in recurrent prostate carcinoma", JOURNAL OF NUCLEAR MEDICINE, vol. 51, no. SUPPL. 2, 2010, XP055503343, Retrieved from the Internet
TADE, F. ET AL.: "Preliminary findings of anti- [18F] FACBC (FACBC) PET-CT imaging of breast cancer", JOURNAL OF NUCLEAR MEDICINE, vol. 56, no. SUPPL. 3, XP055503495, Retrieved from the Internet
SUZUKI, H. ET AL.: "Diagnostic performance and safety of NMK36 (trans-1-amino-3- [18F]fluorocyclobutanecarboxylic acid)-PET/CT in primary prostate cancer: multicenter Phase IIb clinical trial", JAPANESE JOURNAL OF CLINICAL ONCOLOGY, vol. 46, no. 2, February 2016 (2016-02-01), pages 152 - 162, XP055332959
OKA, S. ET AL.: "Feasibility of Fluciclovine (FACBC) for bone metastasis diagnosis in prostate and breast cancer: Evaluation by using triple-tracer autoradiography with 14C-Fluciclovine/3H-FDG/99mTc-HMDP in rat osteolytic/osteoblastic bone metastasis models", JOURNAL OF NUCLEAR MEDICINE, vol. 57, no. SUPPL. 2, 1 May 2016 (2016-05-01), XP002771373, Retrieved from the Internet [retrieved on 20160802]
See also references of EP 3302581A4
SHUSTER, D. ET AL.: "Report of a clinical trial of anti-1 amino 3 [18F]fluorocyclobutane-1- carboxylic acid (anti-[18F]FACBC) PET-CT in recurrent prostate carcinoma", JOURNAL OF NUCLEAR MEDICINE, vol. 51, no. SUPPL. 2, 2010, XP055503343, Retrieved from the Internet
TADE, F. ET AL.: "Preliminary findings of anti- [18F] FACBC (FACBC) PET-CT imaging of breast cancer", JOURNAL OF NUCLEAR MEDICINE, vol. 56, no. SUPPL. 3, XP055503495, Retrieved from the Internet
SUZUKI, H. ET AL.: "Diagnostic performance and safety of NMK36 (trans-1-amino-3- [18F]fluorocyclobutanecarboxylic acid)-PET/CT in primary prostate cancer: multicenter Phase IIb clinical trial", JAPANESE JOURNAL OF CLINICAL ONCOLOGY, vol. 46, no. 2, February 2016 (2016-02-01), pages 152 - 162, XP055332959
OKA, S. ET AL.: "Feasibility of Fluciclovine (FACBC) for bone metastasis diagnosis in prostate and breast cancer: Evaluation by using triple-tracer autoradiography with 14C-Fluciclovine/3H-FDG/99mTc-HMDP in rat osteolytic/osteoblastic bone metastasis models", JOURNAL OF NUCLEAR MEDICINE, vol. 57, no. SUPPL. 2, 1 May 2016 (2016-05-01), XP002771373, Retrieved from the Internet
See also references of EP 3302581A4
Attorney, Agent or Firm:
IDE, Masatake (9F Gobancho Grand Bldg., 3-1, Gobancho, Chiyoda-k, Tokyo 76, JP)
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