Title:
DIAGNOSTIC MARKER
Document Type and Number:
WIPO Patent Application WO/1996/023525
Kind Code:
A1
Abstract:
A diagnostic marker comprising (a) a system for assaying, for example, an antibody and (b) a fluorescent functional group represented by general formula (I) which is bonded to this assay system, wherein R1 and R2 independently represent hydrogen, alkyl, etc.; R3 represents alkyl, alkyl sulfonate, etc.; X- represents, if required, an anionic species; and Y represents C1-10 alkylene optionally containing one or more atoms selected from among oxygen, nitrogen and sulfur. When irradiated with near or far infrared rays, the marker fluoresces a light of 780 nm or more in wavelength, which makes it useful in infrared endoscopy, the identification of the focus in a surgical operation, etc.
Inventors:
ITO SUSUMU (JP)
NOZAWA MASAYUKI (JP)
SHIGA MASANOBU (JP)
SASAMOTO KASUMI (JP)
TAKESAKO KAZUHIRO (JP)
TAKEUCHI HIROSHI (JP)
NOZAWA MASAYUKI (JP)
SHIGA MASANOBU (JP)
SASAMOTO KASUMI (JP)
TAKESAKO KAZUHIRO (JP)
TAKEUCHI HIROSHI (JP)
Application Number:
PCT/JP1996/000169
Publication Date:
August 08, 1996
Filing Date:
January 30, 1996
Export Citation:
Assignee:
DAIICHI PURE CHEMICALS CO LTD (JP)
ITO SUSUMU (JP)
NOZAWA MASAYUKI (JP)
SHIGA MASANOBU (JP)
SASAMOTO KASUMI (JP)
TAKESAKO KAZUHIRO (JP)
TAKEUCHI HIROSHI (JP)
ITO SUSUMU (JP)
NOZAWA MASAYUKI (JP)
SHIGA MASANOBU (JP)
SASAMOTO KASUMI (JP)
TAKESAKO KAZUHIRO (JP)
TAKEUCHI HIROSHI (JP)
International Classes:
A61K49/00; C07D209/60; C07D403/14; C09B23/08; G01N33/533; (IPC1-7): A61K49/00; G01N31/22; G01N21/76; C07D209/60; C07D403/14; C09B62/00
Domestic Patent References:
| WO1995002699A1 | 1995-01-26 | |||
| WO1992000106A2 | 1992-01-09 |
Foreign References:
| JPH07103983A | 1995-04-21 | |||
| JPH0783925A | 1995-03-31 | |||
| JPH06222059A | 1994-08-12 | |||
| JPH06118081A | 1994-04-28 |
Other References:
See also references of EP 0800831A4
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