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Title:
DIAGNOSTIC FOR MATERNAL RISK OF HAVING A CHILD WITH AUTISM SPECTRUM DISORDER
Document Type and Number:
WIPO Patent Application WO/2020/206447
Kind Code:
A3
Abstract:
Provided herein are methods of obtaining and applying measurements of metabolites to quantifying maternal risk of having a child with autism spectrum disorder (ASD), with high specificity and sensitivity.

Inventors:
ADAMS JAMES B (US)
HAHN JUERGEN (US)
Application Number:
PCT/US2020/026915
Publication Date:
November 12, 2020
Filing Date:
April 06, 2020
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Assignee:
UNIV ARIZONA STATE (US)
RENSSELAER POLYTECH INST (US)
International Classes:
C12Q1/6872; A61B5/00; C07K5/078; G01N33/68
Domestic Patent References:
WO2014018774A12014-01-30
WO2019027929A12019-02-07
WO2015157407A12015-10-15
WO2015157601A12015-10-15
Foreign References:
US7897356B22011-03-01
Other References:
HOLLOWOOD, K ET AL.: "Maternal metabolic profile predicts high or low risk of an autism pregnancy outcome", RESEARCH IN AUTISM SPECTRUM DISORDERS, vol. 56, December 2018 (2018-12-01), pages 72 - 82, XP055759497
DATABASE CHEBI [online] 4 June 2013 (2013-06-04), "His-Glu", XP055759515, retrieved from EMBL-EBI Database accession no. 73928
Attorney, Agent or Firm:
NEALEY, Tara A. et al. (US)
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