Title:
DIAGNOSTIC METHOD AND PROGNOSIS PREDICTION METHOD FOR BRAIN DISORDERS AND KIT FOR USE IN SAID METHODS
Document Type and Number:
WIPO Patent Application WO/2013/099827
Kind Code:
A1
Abstract:
The present invention provides the following: a test method for diagnosing brain tumors or cerebrovascular damage, said method being characterized by measuring the amount of FABP7 in a bodily fluid collected from a subject; and a test kit for diagnosing brain tumors or cerebrovascular damage, said test kit comprising an antibody that specifically binds to human FABP7 and an instrument and/or reagent for collecting a bodily fluid.
Inventors:
OWADA YUJI (JP)
SUZUKI MICHIYASU (JP)
KASHIWABARA SHOJI (JP)
SUZUKI MICHIYASU (JP)
KASHIWABARA SHOJI (JP)
Application Number:
PCT/JP2012/083381
Publication Date:
July 04, 2013
Filing Date:
December 25, 2012
Export Citation:
Assignee:
UNIV YAMAGUCHI (JP)
DS PHARMA BIOMEDICAL CO LTD (JP)
DS PHARMA BIOMEDICAL CO LTD (JP)
International Classes:
G01N33/68; G01N33/53; G01N33/574
Other References:
NOBUKO TOKUDA ET AL.: "Shibosan Ketsugo Tanpakushitsu", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 68, no. IS.1, 28 January 2010 (2010-01-28), pages 80 - 82
MAULICE M.A.L. PELSERS ET AL.: "Brain- and Heart- Type Fatty acid-Binding Proteins in the Brain: Tissue Distribution and Clinical Utility", CLIN. CHEM., vol. 50, no. 9, September 2004 (2004-09-01), pages 1568 - 1575, XP055073594
YUJI OWADA: "Nogata Shibosan Ketsugo Tanpaku", SEITAI NO KAGAKU, vol. 55, no. 5, September 2004 (2004-09-01), pages 488 - 489
ROSELINE GODBOUT ET AL.: "Correlation of B-FABP and GFAP expression in malignant glioma", ONCOGENE, vol. 16, no. 15, 16 April 1998 (1998-04-16), pages 1955 - 1962, XP055073595
RAJA MITA ET AL.: "Brain Fatty Acid-binding Protein and w-3/w-6 Fatty Acids MECHANISTIC INSIGHT INTO MALIGNANT GLIOMA CELL MIGRATION", J. BIOL. CHEM., vol. 285, no. 47, 19 November 2010 (2010-11-19), pages 37005 - 37015, XP055073597
MAULICE M.A.L. PELSERS ET AL.: "Brain- and Heart- Type Fatty acid-Binding Proteins in the Brain: Tissue Distribution and Clinical Utility", CLIN. CHEM., vol. 50, no. 9, September 2004 (2004-09-01), pages 1568 - 1575, XP055073594
YUJI OWADA: "Nogata Shibosan Ketsugo Tanpaku", SEITAI NO KAGAKU, vol. 55, no. 5, September 2004 (2004-09-01), pages 488 - 489
ROSELINE GODBOUT ET AL.: "Correlation of B-FABP and GFAP expression in malignant glioma", ONCOGENE, vol. 16, no. 15, 16 April 1998 (1998-04-16), pages 1955 - 1962, XP055073595
RAJA MITA ET AL.: "Brain Fatty Acid-binding Protein and w-3/w-6 Fatty Acids MECHANISTIC INSIGHT INTO MALIGNANT GLIOMA CELL MIGRATION", J. BIOL. CHEM., vol. 285, no. 47, 19 November 2010 (2010-11-19), pages 37005 - 37015, XP055073597
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
Download PDF:
Claims:
Previous Patent: MIXING AND DISPERSION SYSTEM
Next Patent: THERMOPLASTIC RESIN MOLDED ARTICLE HAVING HOLLOW PORTION AND METHOD FOR MANUFACTURING SAME
Next Patent: THERMOPLASTIC RESIN MOLDED ARTICLE HAVING HOLLOW PORTION AND METHOD FOR MANUFACTURING SAME