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Patent Searching and Data


Title:
DIARYL AND ARYLHETEROARYL UREA DERIVATIVES FOR THE PROPHYLAXIS AND TREATMENT OF HALLUCINATIONS ASSOCIATED WITH A NEURODEGENERATIVE DISEASE
Document Type and Number:
WIPO Patent Application WO/2017/011767
Kind Code:
A3
Abstract:
The present invention relates to certain pyrazole derivatives of Formula (I) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor and their uses for the treatment and prophylaxis of visual hallucinations associated with Lewy Body dementia.

Inventors:
FRIEDHOFF LAWRENCE TIM (US)
RAMASWAMY SHANKAR (US)
WEN YANDONG (US)
Application Number:
US2016/042556
Publication Date:
April 06, 2017
Filing Date:
July 15, 2016
Export Citation:
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Assignee:
AXOVANT SCIENCES LTD (GB)
FRIEDHOFF LAWRENCE TIM (US)
RAMASWAMY SHANKAR (US)
WEN YANDONG (US)
International Classes:
A61K31/415; C07C275/28; C07D231/16
Domestic Patent References:
WO2014085362A12014-06-05
WO2014065437A12014-05-01
Foreign References:
US20110207791A12011-08-25
US20070293539A12007-12-20
US20130331399A12013-12-12
US20140349976A12014-11-27
US20150073141A12015-03-12
US20080194836A12008-08-14
Other References:
See also references of EP 3322415A4
Attorney, Agent or Firm:
QUEIROZ DE OLIVEIRA, Pierre et al. (500 Grant StreetSuite 500, Pittsburgh Pennsylvania, US)
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