DIARYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS

Title:

DIARYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS

Document Type and Number:

WIPO Patent Application WO2004022529

Kind Code:

A3

Abstract:

The present invention relates to novel diarylurea derivatives represented by general formula (I) useful as chloride channel blockers. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of bone metabolic diseases, diseases responsive to modulation of the mast cell or basophil activity, diseases responsive to inhibition of angiogenesis, or sickle cell anaemia, and to pharmaceutical compositions comprising the compounds of the invention.

More Like This:

JPH0717951	PRODUCTION OF URETHANE COMPOUND
JP2004182657	AGENT FOR PROMOTING ELEVATION OF HDL LEVEL
WO/1995/028396	PHENOL DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE, ESPECIALLY IN NON-LINEAR OPTICS

Inventors:

DAHL BJARNE H (DK)
CHRISTOPHERSEN PALLE (DK)
ENGSIG MICHAEL THYRRING (DK)
KARSDAL MORTEN ASSER (DK)
FOGED NIELS TAEKKER (DK)
JENSEN FLEMMING REISSIG (DK)

Application Number:

PCT/DK2003/000575

Publication Date:

May 13, 2004

Filing Date:

September 04, 2003

Export Citation:

Click for automatic bibliography generation Help

Assignee:

NEUROSEARCH AS (DK)
DAHL BJARNE H (DK)
CHRISTOPHERSEN PALLE (DK)
ENGSIG MICHAEL THYRRING (DK)
KARSDAL MORTEN ASSER (DK)
FOGED NIELS TAEKKER (DK)
JENSEN FLEMMING REISSIG (DK)

International Classes:

C07D277/20; A61K31/17; A61K31/19; A61K31/192; A61K31/401; A61K31/41; A61K31/426; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/661; A61K31/69; A61P1/04; A61P1/12; A61P7/06; A61P9/00; A61P9/10; A61P9/12; A61P11/06; A61P13/00; A61P17/00; A61P17/06; A61P17/08; A61P17/10; A61P19/00; A61P27/02; A61P27/06; A61P29/00; A61P35/00; A61P35/04; A61P37/08; A61P43/00; C07C275/26; C07C275/30; C07C275/42; C07D207/16; C07D209/40; C07D213/75; C07D213/81; C07D213/82; C07D231/40; C07D257/04; C07D277/48; C07D295/192; C07D307/68; C07D333/36; C07D401/12; C07F5/02; C07F9/38; C07F9/58; (IPC1-7): C07C275/26; C07C275/28; C07D257/04; C07D207/00; A61K31/17; A61K31/41; A61P19/00; A61P43/00

Domestic Patent References:

WO2003000245A1	2003-01-03
WO2002039987A2	2002-05-23
WO1998047879A1	1998-10-29
WO2000024707A1	2000-05-04
WO1997045400A1	1997-12-04
WO2002064128A1	2002-08-22
WO1997045111A1	1997-12-04
WO1994022807A1	1994-10-13
WO2001012188A1	2001-02-22
WO2001076530A2	2001-10-18
WO2002092576A1	2002-11-21

Download PDF:

View/Download PDF PDF Help

Previous Patent: ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS

Next Patent: GENTLE SULPHATING METHOD