Title:
DIBENZOCYCLOOCTANE COMPOUND AND RETROVIRUS INFECTION REMEDY CONTAINING THE SAME AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/1995/000466
Kind Code:
A1
Abstract:
A dibenzocyclooctane compound, represented by general formula (I), useful as medicines such as an antiretroviral agent and intermediates for other medecines, wherein each R represents hydrogen, lower alkyl, or optionally substituted phenyl or alkylcarbonyl, or alternatively one of Rs is combined with the neighboring R to form lower alkylene; each R' represents lower alkyl; each Y represents hydrogen, halogen, alkyl, lower alkyloxy, acyl, formyl, hydroxy, cyano or di(lower alkyl)amino; and each R1 represents hydrogen, optionally substituted lower alkyl, optionally substituted aralkyl, lower alkoxy, aminocarbonyl, acyl, sulfonyl or phosphoryl, provided when R1 represents hydrogen or lower alkyl, then at least one Y does not represent hydrogen.
Inventors:
TANAKA MASAHIDE (JP)
SAKATA TOSHIYA (JP)
IKEYA YUKINOBU (JP)
KATO AKIHISA (JP)
MORI KAZUYA (JP)
WAKAMATSU TAKESHI (JP)
FUJIHASHI TOSHIAKI (JP)
KAJI AKIRA (JP)
KAJI HIDEKO (JP)
SAKATA TOSHIYA (JP)
IKEYA YUKINOBU (JP)
KATO AKIHISA (JP)
MORI KAZUYA (JP)
WAKAMATSU TAKESHI (JP)
FUJIHASHI TOSHIAKI (JP)
KAJI AKIRA (JP)
KAJI HIDEKO (JP)
Application Number:
PCT/JP1994/000990
Publication Date:
January 05, 1995
Filing Date:
June 21, 1994
Export Citation:
Assignee:
TSUMURA & CO (JP)
TANAKA MASAHIDE (JP)
SAKATA TOSHIYA (JP)
IKEYA YUKINOBU (JP)
KATO AKIHISA (JP)
MORI KAZUYA (JP)
WAKAMATSU TAKESHI (JP)
FUJIHASHI TOSHIAKI (JP)
AKIRA KAJI (JP)
KAJI HIDEKO (JP)
TANAKA MASAHIDE (JP)
SAKATA TOSHIYA (JP)
IKEYA YUKINOBU (JP)
KATO AKIHISA (JP)
MORI KAZUYA (JP)
WAKAMATSU TAKESHI (JP)
FUJIHASHI TOSHIAKI (JP)
AKIRA KAJI (JP)
KAJI HIDEKO (JP)
International Classes:
C07C39/14; C07C43/20; C07C47/57; C07C47/575; C07C49/83; C07C49/84; C07C69/00; C07C255/53; C07C255/54; (IPC1-7): C07C39/17; A61K31/05; A61K31/085; A61K31/16; A61K31/21; A61K31/275; A61K31/325; A61K31/495; A61K31/66; C07C39/42; C07C43/20; C07C43/257; C07C47/52; C07C69/035; C07C215/64; C07C217/74; C07C219/28; C07C255/49; C07C271/40; C07C309/65; C07C309/73; C07D295/20; C07F9/32
Foreign References:
| JPH05301843A | 1993-11-16 | |||
| JPH02169543A | 1990-06-29 |
Other References:
CHEM. PHARM. BULL., Vol. 27, No. 7, 1979, IKEYA Y. et al., "The Constituents of Schizandra Chinensis Baill. IV. The Structures of Two New Lignans, Pregomisin and Gomisin J", pages 1583-8.
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