Title:
DICER SUBSTRATE RNA PEPTIDE CONJUGATES AND METHODS FOR RNA THERAPEUTICS
Document Type and Number:
WIPO Patent Application WO2008022046
Kind Code:
B1
Abstract:
Dicer substrate RNA peptide conjugates comprising a double stranded ribonucleic acid (dsRNA) having a sense strand and an antisense strand, and a peptide, wherein the dicer substrate RNA is conjugated to the peptide, and compositions and methods of uses thereof.
Inventors:
QUAY STEVEN C (US)
JOHNSON PAUL HICKOK (US)
HOUSTON MICHAEL E JR (US)
ADAMI ROGER C (US)
FAM RENATA (US)
JOHNSON PAUL HICKOK (US)
HOUSTON MICHAEL E JR (US)
ADAMI ROGER C (US)
FAM RENATA (US)
Application Number:
PCT/US2007/075744
Publication Date:
July 10, 2008
Filing Date:
August 10, 2007
Export Citation:
Assignee:
NASTECH PHARM CO (US)
QUAY STEVEN C (US)
JOHNSON PAUL HICKOK (US)
HOUSTON MICHAEL E JR (US)
ADAMI ROGER C (US)
FAM RENATA (US)
QUAY STEVEN C (US)
JOHNSON PAUL HICKOK (US)
HOUSTON MICHAEL E JR (US)
ADAMI ROGER C (US)
FAM RENATA (US)
International Classes:
C07D213/74; A61K31/4418; A61K31/4427; A61K31/444; A61K31/4965; A61K31/497; A61K31/5377; A61K31/55; A61K31/551; C07D241/20; C07D401/04; C07D401/10; C07D401/14; C07D403/04; C07D413/04; C12N15/11; C12N15/113
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