Title:
DIGESTIVE TRACT DETOXICANT FOR VERTEBRATES
Document Type and Number:
WIPO Patent Application WO/2012/064230
Kind Code:
A3
Abstract:
A sorbent selected from a group of reversed-phase liquid chromatography sorbents is proposed as a digestive tract detoxicant for vertebrates, said sorbent being a hydrophobizated matrix of polysilicic acid gel having the general approximate formula (Н2О)v{(SiO~2)x(ОH)yRz}w, in which the ratio of z/y varies from 79/21 to 1/99, where: v is the amount of water physically sorbed; x is the number of silica atoms in the gel structure; y is the number of silanol groups in the structure and on the surface of the gel; z is the number of aliphatic or aromatic substituents; R is a hydrocarbon radical which is bound to a silicate base by the covalent bond Si-C, Si-O-C or Si-NX-C and is comprised of linear or branched alkyl or fluoroalkyl residues with 2 to 24 carbon atoms, containing from 1 to 4 isolated or adjacent double bonds, or of a cyclic substituent having the general formula Ar(СН2)n-, in which Ar is an aromatic or alicyclic monocyclic or polycyclic substituent with 6 to 24 carbon atoms, where the values of n are from 0 to 6 and the ratio of v/w is from 0 to 95. The proposed detoxicants exhibit a high degree of hydrophobicity and effectiveness and are easy to take.
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Inventors:
SOTNICHENKO ALEKSANDR IVANOVICH (RU)
Application Number:
PCT/RU2011/000877
Publication Date:
July 26, 2012
Filing Date:
November 09, 2011
Export Citation:
Assignee:
SOTNICHENKO ALEKSANDR IVANOVICH (RU)
International Classes:
A61K31/695; A61P1/00; A61P39/00
Foreign References:
| GB2037296A | 1980-07-09 | |||
| RU2234931C2 | 2004-08-27 | |||
| RU2293744C1 | 2007-02-20 |
Other References:
VANSANT E.F. ET AL.: "Characterization and chemical modification of the silica surface", ELSEVIER SCIENCE B.V., vol. 93, 1995, pages 154 - 158, Retrieved from the Internet
Attorney, Agent or Firm:
LIMITED LIABILITY COMPANY INTELLECTUAL PROPERTY AGENCY "TECHNEED" (Moscow, 7, RU)
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