DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Title:

DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/121844

Kind Code:

A1

Abstract:

Disclosed are a dihydropyrimidine compound, a preparation method therefor, and an application thereof. Provided are a dihydropyrimidine compound as shown in formula I or a pharmaceutically acceptable salt thereof. The dihydropyrimidine compound has good anti-HBV activity and lower cytotoxicity, and can be used to prepare drugs for treating and/or preventing HBV infection.

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Inventors:

TANG GUOZHI (CN)
MA DAWEI (CN)
CHEN JUNLI (CN)
HUANG MENGWEI (CN)
ZHANG JINLIANG (CN)

Application Number:

PCT/CN2021/135751

Publication Date:

June 16, 2022

Filing Date:

December 06, 2021

Export Citation:

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Assignee:

SHANGHAI VISONPHARMA CO LTD (CN)

International Classes:

A61K31/506; C07D471/04; A61P31/20

Domestic Patent References:

WO2020125729A1	2020-06-25
WO2020135439A1	2020-07-02

Foreign References:

CN106061978A	2016-10-26
CN109843296A	2019-06-04
CN109678859A	2019-04-26
CN107427514A	2017-12-01

Other References:

DATABASE REGISTRY ANONYMOUS : "1H-Pyrrolo[3,4-c]pyridin-1-one, octahydro-3,3-dimethyl- (CA INDEX NAME) OTHER CA INDEX NAMES: CN - Octahydro-3,3-dimethyl-1H-pyrrolo[3,4-c]pyridin-1-one MF - C9 H16 N2 O SR - Chemical Catalog Supplier: FCH Group LC - STN Files: CHEMCATS tektronix-4QCUHO2S ", XP055943371, retrieved from STN

Attorney, Agent or Firm:

SHANGHAI BESINGIP INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)

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