Title:
DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE
Document Type and Number:
WIPO Patent Application WO/2019/001396
Kind Code:
A1
Abstract:
Provided herein are a dihydropyrimidine compound and a pharmaceutical application thereof, especially the application used for treating and preventing HBV diseases. Specifically, provided herein is a compound having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof, wherein the variables of the formulas are as defined in the specification. Also provided herein is use of the compound having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof as a medicine, especially for treating and preventing HBV diseases.
Inventors:
REN QINGYUN (CN)
LIU XINCHANG (CN)
HUANG JIANZHOU (CN)
ZHANG YINGJUN (CN)
GOLDMANN SIEGFRIED (CN)
LIU XINCHANG (CN)
HUANG JIANZHOU (CN)
ZHANG YINGJUN (CN)
GOLDMANN SIEGFRIED (CN)
Application Number:
PCT/CN2018/092699
Publication Date:
January 03, 2019
Filing Date:
June 25, 2018
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D417/14; A61K31/426; A61K31/4985; A61K31/506; A61P1/16; A61P31/12; C07D239/20; C07D487/04
Domestic Patent References:
| WO2015074546A1 | 2015-05-28 |
Foreign References:
| CN106061978A | 2016-10-26 | |||
| CN103664897A | 2014-03-26 |
Other References:
SCIENCE, vol. 299, 2003, pages 893 - 896
See also references of EP 3658554A4
See also references of EP 3658554A4
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