Title:
DIPYRIDYL ALKALOID, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/090891
Kind Code:
A1
Abstract:
Disclosed are a dipyridyl alkaloid, a preparation method therefor and a use thereof, the structure of the dipyridyl alkaloid is as shown in formula I. The dipyridyl alkaloid has a tumour cell proliferation inhibitory activity and can be used as a tumour cell proliferation inhibitor or for developing an anti-tumour drug.
Inventors:
ZHU WEIMING (CN)
MEI XIANGUI (CN)
FU PENG (CN)
WANG YI (CN)
LIU PEIPEI (CN)
MEI XIANGUI (CN)
FU PENG (CN)
WANG YI (CN)
LIU PEIPEI (CN)
Application Number:
PCT/CN2017/110799
Publication Date:
May 24, 2018
Filing Date:
November 14, 2017
Export Citation:
Assignee:
OCEAN UNIV CHINA (CN)
International Classes:
C07D405/14; A61K31/444; A61P35/00; C07D213/68; C07D213/69; C12P17/16
Other References:
FU PENG: "Antibiotic Compounds from Four Marine-Derived Actinomycete Strains", CHINA DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, MEDICINE AND HEALTH SCIENCES, 15 January 2014 (2014-01-15), ISSN: 1674-022X
FU PENG: "Four Marine-Derived Actinomycete Strains", CHINA DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, MEDICINE AND HEALTH SCIENCES, 15 January 2014 (2014-01-15), ISSN: 1674-022X
MCINNES, A.G. ET AL.: "Caerulomycins B and C, new 2, 2'-dipyridyl derivatives from Streptomyces caeruleus", CANADIAN JOURNAL OF CHEMISTRY, vol. 55, no. 24, 15 December 1977 (1977-12-15), pages 4159 - 4165, XP055503091
FU, PENG ET AL.: "Acyclic Congeners from Actinoalloteichus cyanogriseus provide insights into cyclic bipyridine glycoside formation", ORGANIC LETTERS, vol. 16, no. ยง6, 15 August 2014 (2014-08-15), pages 4264 - 4267, XP055503092, ISSN: 1523-7060
JIA HAIJIAN: "Fermentation optimization for the production of caerulomycin A from marine-derived Actinoalloteichus cyanogriseus WH1-2216-6", CHINA MASTER'S THESES FULL-TEXT DATABASE, ENGINEERING TECHNOLOGY, 15 January 2014 (2014-01-15), pages 3 - 418-23 -24-26 -28-30, ISSN: 1674-0246
FU PENG: "Four Marine-Derived Actinomycete Strains", CHINA DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, MEDICINE AND HEALTH SCIENCES, 15 January 2014 (2014-01-15), ISSN: 1674-022X
MCINNES, A.G. ET AL.: "Caerulomycins B and C, new 2, 2'-dipyridyl derivatives from Streptomyces caeruleus", CANADIAN JOURNAL OF CHEMISTRY, vol. 55, no. 24, 15 December 1977 (1977-12-15), pages 4159 - 4165, XP055503091
FU, PENG ET AL.: "Acyclic Congeners from Actinoalloteichus cyanogriseus provide insights into cyclic bipyridine glycoside formation", ORGANIC LETTERS, vol. 16, no. ยง6, 15 August 2014 (2014-08-15), pages 4264 - 4267, XP055503092, ISSN: 1523-7060
JIA HAIJIAN: "Fermentation optimization for the production of caerulomycin A from marine-derived Actinoalloteichus cyanogriseus WH1-2216-6", CHINA MASTER'S THESES FULL-TEXT DATABASE, ENGINEERING TECHNOLOGY, 15 January 2014 (2014-01-15), pages 3 - 418-23 -24-26 -28-30, ISSN: 1674-0246
Attorney, Agent or Firm:
BEIJING TANLULAI PATENT AGENT LTD (CN)
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