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Patent Searching and Data


Title:
DISEASE DEVELOPMENT DETERMINATION DEVICE, DISEASE DEVELOPMENT DETERMINATION METHOD, AND DISEASE DEVELOPMENT DETERMINATION PROGRAM
Document Type and Number:
WIPO Patent Application WO/2018/079840
Kind Code:
A1
Abstract:
[Problem] To enable disease development determination through learning performed via a neural network with use of data of the expression levels of biomarkers, and enable extraction of a biomarker that is characteristic of a disease via the neural network. [Solution] According to the present invention: a sample data set is acquired in which the expression levels are recorded of a plurality of types of respective biomarkers, for each individual; a learned model is generated which enables disease development determination and which is pre-acquired through machine learning with use of training data; a plurality of the sample data sets, to which label information indicating that a disease is developed is provided, are inputted to the learned model so that calculation is performed; the degrees of importance are numerically represented of features of the plurality of respective biomarkers acquired through the learned model by the development determination calculation, for each of the sample data sets; and a predetermined number of biomarkers are extracted as biomarkers that are characteristic of the disease, on the basis of the degrees of importance obtained by numerically representing all of the sample data sets for each of the biomarkers.

Inventors:
OKANOHARA DAISUKE (JP)
OONO KENTA (JP)
OTA NOBUYUKI (US)
HAMZAOUI KARIM (JP)
AKIBA TAKUYA (JP)
Application Number:
JP2017/039363
Publication Date:
May 03, 2018
Filing Date:
October 31, 2017
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Assignee:
PREFERRED NETWORKS INC (?1000004, JP)
International Classes:
G06F19/24; C12M1/34; C12Q1/68
Foreign References:
JP2014511677A2014-05-19
JP2012523000A2012-09-27
JP2012073761A2012-04-12
JP2006526487A2006-11-24
JP2012508577A2012-04-12
JP2001083986A2001-03-30
Attorney, Agent or Firm:
SUDO Yutaka et al. (?1510053, JP)
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