Title:
DISPOSABLE INTRANASAL BRAIN-TARGETING DRUG DELIVERY APPARATUS
Document Type and Number:
WIPO Patent Application WO/2016/138795
Kind Code:
A1
Abstract:
A disposable intranasal brain-targeting drug delivery apparatus comprising an administering apparatus. The administering apparatus comprises a container (1) having a cavity and used for accommodating an agent, a catheter (2) in communication with the container (1) and used for introducing the agent in the container (1) into the nasal cavity, and a spray nozzle (4) arranged at an extremity of the catheter (2). The extremity of the catheter (2) can be extended into the olfactory area above a horizontal position corresponding to the middle nasal concha. The administering apparatus also comprises a pressure-sensitive film (3) that is arranged within the container (1), is used for separating the cavity of the container (1) into multiple discrete cavities (8 and 9), and ruptures under pressure. The other extremity of the catheter (2) is connected to one among the multiple cavities (8 and 9). The administering apparatus also comprises a soluble film (9) that is used for separating a lumen of the catheter (2) from the cavity (8) connected thereto and dissolves either partially or completely upon contact with the agent. The drug delivery apparatus allows highly efficient delivery of the agent to the olfactory area for direct absorption by the brain, thus providing therapeutic effects to the central nervous system.
Inventors:
QIAN MINGXIN (CN)
HE RENYANG (CN)
SHI JUNWEI (CN)
HE RENYANG (CN)
SHI JUNWEI (CN)
Application Number:
PCT/CN2015/100099
Publication Date:
September 09, 2016
Filing Date:
December 31, 2015
Export Citation:
Assignee:
TONGLI BIOMEDICAL CO LTD (CN)
International Classes:
A61M11/00
Foreign References:
| CN204446845U | 2015-07-08 | |||
| CN104667391A | 2015-06-03 | |||
| CN204446847U | 2015-07-08 | |||
| CN102482023A | 2012-05-30 | |||
| CN1607968A | 2005-04-20 | |||
| CN103282069A | 2013-09-04 | |||
| CN201105005Y | 2008-08-27 | |||
| US5284132A | 1994-02-08 |
Attorney, Agent or Firm:
SUZHOU CREATOR PATENT &TRADEMARK AGENCY LTD. (CN)
苏州创元专利商标事务所有限公司 (CN)
苏州创元专利商标事务所有限公司 (CN)
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