Title:
DISUBSTITUTED CHALCONE OXIMES AS SELECTIVE AGONISTS OF RARgamma RETINOID RECEPTORS
Document Type and Number:
WIPO Patent Application WO2005066116
Kind Code:
A8
Abstract:
Compounds of the formula where the variables are as defined in the specification, are useful for preventing or treating emphysema and related pulmonary conditions of mammals and other diseases and conditions which are responsive to RARgamma agonist retinoids, such as skin related diseases, including but not limited to acne and psoriasis.
Inventors:
TSANG KWOK YIN (US)
SINHA SANTOSH (US)
LIU XIAOXIA (US)
BHAT SMITA (US)
CHANDRARATNA ROSHANTHA A (US)
SINHA SANTOSH (US)
LIU XIAOXIA (US)
BHAT SMITA (US)
CHANDRARATNA ROSHANTHA A (US)
Application Number:
PCT/US2004/043148
Publication Date:
October 20, 2005
Filing Date:
December 21, 2004
Export Citation:
Assignee:
ALLERGAN INC (US)
TSANG KWOK YIN (US)
SINHA SANTOSH (US)
LIU XIAOXIA (US)
BHAT SMITA (US)
CHANDRARATNA ROSHANTHA A (US)
TSANG KWOK YIN (US)
SINHA SANTOSH (US)
LIU XIAOXIA (US)
BHAT SMITA (US)
CHANDRARATNA ROSHANTHA A (US)
International Classes:
A61K31/15; A61K31/4706; A61K31/498; C07C251/40; C07D215/227; C07D241/40; C07D241/42; C07D307/81; C07D307/87; C07D311/58; C07D335/06; (IPC1-7): C07C251/40; C07D215/22; C07D241/42; C07D307/81; C07D307/87; C07D311/58; C07D335/06; A61K31/15; A61K31/343; A61K31/353; A61K31/382; A61K31/4704; A61K31/498; A61P11/00; A61P17/06
Download PDF: