Title:
DNA APTAMER BINDING SPECIFICALLY TO ODAM AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/112178
Kind Code:
A1
Abstract:
The present invention relates to a nucleic acid aptamer binding specifically to odontogenic ameloblast-associated protein (ODAM) and a use thereof. According to the present invention, a nucleic acid aptamer for detecting ODAM, and a method, a composition, a sensor, and a kit for detecting ODAM, each comprising the same aptamer, are useful for detecting ODAM present in a sample on the basis of the high specificity and affinity of the ODAM aptamer for ODAM.
Inventors:
GU MAN BOCK (KR)
LEE BANG-HYUN (KR)
LEE BANG-HYUN (KR)
Application Number:
PCT/KR2018/012958
Publication Date:
June 13, 2019
Filing Date:
October 30, 2018
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
C12N15/115; G01N33/543; G01N33/68
Domestic Patent References:
| WO2012122640A1 | 2012-09-20 |
Foreign References:
| KR20160101889A | 2016-08-26 | |||
| KR20130024551A | 2013-03-08 | |||
| KR20110104805A | 2011-09-23 | |||
| KR20150052311A | 2015-05-13 |
Other References:
LEE, BANG HYUN ET AL.: "The Sensitive Detection of ODAM by Using Sandwich-type Biosensors with a Cognate Pair of Aptamers for the Early Diagnosis of Periodontal Disease", BIOSENSORS AN D BIOELECTRONICS, vol. 126, 23 October 2018 (2018-10-23), pages 122 - 128, XP085574362, DOI: doi:10.1016/j.bios.2018.10.040
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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