Title:
DNA-DEPENDENT MRI CONTRAST AGENTS
Document Type and Number:
WIPO Patent Application WO2005016387
Kind Code:
A3
Abstract:
The present invention provides magnetic resonance imaging contrast agents comprising a synthetic peptide or polypeptide, and methods to use those agents.
Inventors:
FRANKLIN SONYA (US)
Application Number:
PCT/US2004/026209
Publication Date:
June 09, 2005
Filing Date:
August 12, 2004
Export Citation:
Assignee:
UNIV IOWA RES FOUND (US)
FRANKLIN SONYA (US)
FRANKLIN SONYA (US)
International Classes:
A61K49/00; A61K49/08; A61K49/14; A61K51/08; C12Q1/68; (IPC1-7): A61K49/14; A61K51/08
Domestic Patent References:
| WO2002072807A2 | 2002-09-19 |
Other References:
WELCH J.T ET AL.: "Lanthanide-binding helix-turn-helix peptides : solution structure of a designed metallonuclease.", PNAS, vol. 100, no. 7, 1 April 2003 (2003-04-01), XP002321540
CARAVAN P ET AL: "GADOLINIUM-BINDING HELIX-TURN-HELIX PEPTIDES: DNA-DEPENDENT MRI CONTRAST AGENTS", CHEMICAL COMMUNICATIONS - CHEMCOM, ROYAL SOCIETY OF CHEMISTRY, GB, no. 20, 21 October 2003 (2003-10-21), pages 2574 - 2575, XP008041846, ISSN: 1359-7345
CARAVAN P ET AL: "GADOLINIUM-BINDING HELIX-TURN-HELIX PEPTIDES: DNA-DEPENDENT MRI CONTRAST AGENTS", CHEMICAL COMMUNICATIONS - CHEMCOM, ROYAL SOCIETY OF CHEMISTRY, GB, no. 20, 21 October 2003 (2003-10-21), pages 2574 - 2575, XP008041846, ISSN: 1359-7345
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