Title:
DNA, POLYPEPTIDE, ANTI-MESOTHELIN ANTIBODY, TUMOR IMAGING AGENT AND COMPLEX
Document Type and Number:
WIPO Patent Application WO/2019/087425
Kind Code:
A1
Abstract:
Provided is a DNA comprising any of (a) to (c): (a) a DNA which comprises any of base sequences of from the 16th to 831st positions of SEQ ID NO: 1, from the 16th to 822nd positions of SEQ ID NO: 3, from the 16th to 825th positions of SEQ ID NO: 5, from the 16th to 819th positions of SEQ ID NO: 7, from the 16th to 834th positions of SEQ ID NO: 9 and from the 16th to 828th positions of SEQ ID NO: 11; (b) a DNA which encodes a polypeptide comprising any of amino acid sequences of from the 1st to 272nd positions of SEQ ID NO: 2, from the 1st to 269th positions of SEQ ID NO: 4, from the 1st to 270th positions of SEQ ID NO: 6, from the 1st to 268th positions of SEQ ID NO: 8, from the 1st to 273rd positions of SEQ ID NO: 10 and from the 1st to 271st positions of SEQ ID NO: 12; and (c) a complementary strand of DNA (a) or (b) described above.
Inventors:
MATSUURA EIJI (JP)
KOBAYASHI KAZUKO (JP)
TAKENAKA FUMIAKI (JP)
KOBAYASHI KAZUKO (JP)
TAKENAKA FUMIAKI (JP)
Application Number:
PCT/JP2018/012391
Publication Date:
May 09, 2019
Filing Date:
March 27, 2018
Export Citation:
Assignee:
NAT UNIV CORPORATION OKAYAMA UNIV (JP)
International Classes:
C12N15/13; A61K39/395; A61K47/66; A61K47/68; A61K51/10; A61P35/00; C07K16/30
Domestic Patent References:
| WO1999028471A2 | 1999-06-10 | |||
| WO2010111282A1 | 2010-09-30 |
Foreign References:
| JP2003502030A | 2003-01-21 |
Other References:
KOBAYASHI K. ET AL: "A novel PET imaging using 64Cu-labeled monoclonal antibody against mesothelin commonly expressed on cancer cells", JOURNAL OF IMMUNOLOGY RESEARCH, vol. 2015, 268172, 2015
Matsuura Eiji: Project/Area Number: 23659299, Development of targeted therapy of cancer cells with diagnostic imaging through the application of immunoliposomes, Grants-in-Aid for Scientific Research (Kaken)
TERWISSCHA VAN SCHELTINGA A. ET AL: "Preclinical efficacy of an antibody-drug conjugate targeting mesothelin correlates with quantitative 89ZR- ImmunoPET", MOLECULAR CANCER THERAPEUTICS, vol. 16, no. 1, 19 October 2016 (2016-10-19), pages 134 - 142
Matsuura Eiji: Project/Area Number: 23659299, Development of targeted therapy of cancer cells with diagnostic imaging through the application of immunoliposomes, Grants-in-Aid for Scientific Research (Kaken)
TERWISSCHA VAN SCHELTINGA A. ET AL: "Preclinical efficacy of an antibody-drug conjugate targeting mesothelin correlates with quantitative 89ZR- ImmunoPET", MOLECULAR CANCER THERAPEUTICS, vol. 16, no. 1, 19 October 2016 (2016-10-19), pages 134 - 142
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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