DNA VACCINE COMPOSITION FOR PREVENTING AND TREATING HERPES ZOSTER, AND METHOD FOR ACTIVATING T CELLS FOR VZV ANTIGEN BY USING SAME

WIPO Patent Application WO/2016/064063

A1

The present invention provides a DNA vaccine composition for preventing and treating herpes zoster, containing: at least one type of plasmid containing the insertion site of a varicella-zoster virus (VZV)-derived gene encoding a VZV protein; and other pharmaceutically acceptable ingredients. The plasmid contains a plurality of plasmids containing the insertion site of heterologous genes which are different from each other. The plasmid contains: a first plasmid containing the insertion site of a first gene encoding IE-62 protein (SEQ ID NO: 1); a second plasmid containing the insertion site of a second gene encoding IE-63 protein (SEQ ID NO: 2); and a third plasmid containing the insertion site of a third gene encoding gE protein (SEQ ID NO: 3).

PARK YOUNG KUN (US)
CHO BYUNG MUN (KR)
JEONG MOON SUP (KR)
LEE HYO JIN (KR)
CHO YOUNG RAN (KR)
OH JOO YEON (KR)

PCT/KR2015/006043

April 28, 2016

June 16, 2015

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GENEONE LIFE SCIENCE CO LTD (KR)

A61K48/00; A61P31/22

KR19990082360A

1999-11-25

DATABASE GenBank 14 August 2009 (2009-08-14), Database accession no. BAC44882.1
DATABASE GenBank 16 December 2013 (2013-12-16), Database accession no. AGU41816.1
DATABASE GenBank Database accession no. CAA27951.1
DATABASE GenBank 29 May 2013 (2013-05-29), Database accession no. KC312931.1
See also references of EP 3210631A4

KO, Young Kap et al. (KR)
고영갑 (KR)

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