Title:
DOSING REGIMEN OF THERAPEUTIC AGENT FOR ATAXIA ASSOCIATED WITH SPINOCEREBELLAR DEGENERATION
Document Type and Number:
WIPO Patent Application WO/2016/208045
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a medicinal composition for treating ataxia associated with spinocerebellar degeneration, said medicinal composition reducing a risk of side effects caused by an increase in parathyroid hormone level and being excellent. Provided is a medicinal composition for treating ataxia associated with spinocerebellar degeneration, said medicinal composition being characterized by being to be dosed once a day and containing, as an active ingredient, rovatirelin in a daily dose of 1.6-3.2 mg or a pharmacologically acceptable salt of rovatirelin in a daily dose of 1.6-3.2 mg in terms of a free salt. The medicinal composition according to the present invention is highly useful as a therapeutic agent for ataxia associated with spinocerebellar degeneration.
Inventors:
SHIMIZU YOSHITAKA (JP)
YAMANO HITOSHI (JP)
KIYONO YUJI (JP)
IJIRO TOMOYUKI (JP)
YAMANO HITOSHI (JP)
KIYONO YUJI (JP)
IJIRO TOMOYUKI (JP)
Application Number:
PCT/JP2015/068438
Publication Date:
December 29, 2016
Filing Date:
June 26, 2015
Export Citation:
Assignee:
KISSEI PHARMACEUTICAL (JP)
International Classes:
A61K31/427; A61P25/00
Foreign References:
| JP2008512344A | 2008-04-24 |
Other References:
HAJIME KAINUMA ET AL.: "Clinical Phase I Study of TA-0910. Oral Repeated Dose Study.", JOURNAL OF CLINICAL THERAPEUTICS & MEDICINES, vol. 13, no. 10, June 1997 (1997-06-01), pages 2517 - 2532, XP009504662
Attorney, Agent or Firm:
YANAGI, Nobuko et al. (JP)
Willow Nobuko (JP)
Willow Nobuko (JP)
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