Title:
DRUG-COATED BALLOON
Document Type and Number:
WIPO Patent Application WO/2018/059167
Kind Code:
A1
Abstract:
A drug-coated balloon, comprising a balloon body and a drug coating covering the surface of the balloon body. The drug coating comprises an active drug and a carrier, the active drug comprising an anti-proliferative drug and the carrier comprising a transdermal enhancer. By using the transdermal enhancer which can promote rapid permeation and absorption of drugs as the carrier, the drug rapidly permeates into tissues at diseased locations after being released, so that the absorption rate of the drug in diseased tissues of vascular systems or other body lumens is improved. The defects that in clinical use, after the drug-coated balloon is placed into a human body, the permeation of the drug to a target lesion location is too slow, and the drug flows away due to high-speed blood flow scouring before being absorbed by blood vessels can be solved. Moreover, due to the fact that the drug quantity absorbed by tissues is improved, a large quantity of drugs can be retained in the tunica media, and the drug can take effect continuously to inhibit long-term restenosis.
Inventors:
SONG JINGZHONG (CN)
XIE QIZONG (CN)
XIE QIZONG (CN)
Application Number:
PCT/CN2017/099022
Publication Date:
April 05, 2018
Filing Date:
August 25, 2017
Export Citation:
Assignee:
LIFETECH SCIENT SHENZHEN CO (CN)
International Classes:
A61L29/16; A61L29/08
Foreign References:
| CN103736154A | 2014-04-23 | |||
| CN102883753A | 2013-01-16 | |||
| US20080276935A1 | 2008-11-13 | |||
| EP1121162A1 | 2001-08-08 | |||
| CN101181650A | 2008-05-21 | |||
| CN105228663A | 2016-01-06 |
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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