DRUG COMPOSITION COMPRISING DIPEPTYDYL ALDEHYDE DERIVATIVE

Title:

DRUG COMPOSITION COMPRISING DIPEPTYDYL ALDEHYDE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2002/034252

Kind Code:

A1

Abstract:

A drug composition which comprises a compound represented by the general formula (I), wherein R?1¿ represents an alkyl group having 1 to 4 carbon atoms or represents an aryl group having 6 to 10 carbon atoms optionally having a substituent, R?2¿ and R?3¿ may be the same or different and each represent hydrogen or an alkyl group having 1 to 4 carbon atoms or R?2¿ and R?3¿ may together form a ring having 3 to 7 carbon atoms, and R?4¿ represents an aryl group, a cycloalkyl group or a lower alkyl group optionally substituted with an aromatic heterocyclic residue, or a pharmaceutically acceptable salt of the compound, and a lipid. The drug composition is improved in stability, absobability and the transfer to a target tissue over a conventional composition containing no lipid added.

Inventors:

INOUE JUN (JP)
YAMAGUCHI MASAZUMI (JP)

Application Number:

PCT/JP2001/008514

Publication Date:

May 02, 2002

Filing Date:

September 27, 2001

Export Citation:

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Assignee:

SENJU PHARMA CO (JP)
INOUE JUN (JP)
YAMAGUCHI MASAZUMI (JP)

International Classes:

A61K9/00; A61K9/127; A61K9/48; A61K31/18; A61K31/404; A61K47/02; A61K47/24; A61K47/28; A61K47/48; A61P9/10; A61P19/10; A61P25/00; A61P25/28; A61P27/02; A61P27/06; A61P37/02; (IPC1-7): A61K31/18; A61K31/404; A61K9/127; A61K47/24; A61K47/28; A61P9/10; A61P37/02; A61P25/28; A61P19/10; A61P25/00; A61P27/02; A61P27/06

Domestic Patent References:

WO1990011780A1	1990-10-18
WO1996019211A1	1996-06-27
WO2001026648A1	2001-04-19

Foreign References:

US5506243A	1996-04-09
JPS5838219A	1983-03-05
JPH11199488A	1999-07-27
EP0622072A2	1994-11-02
JPH06329533A	1994-11-29

Other References: