Title:
DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER
Document Type and Number:
WIPO Patent Application WO/1994/018987
Kind Code:
A1
Abstract:
The invention aims at effectively utilizing a single-stranded nucleic acid copolymer, in particular, poly(adenylic acid-uridylic acid) and providing a drug composition having an antitumor effect. An example of the drug composition of the invention is one containing a lipid device, such as Lipofecting, 3-0-(4-dimethylaminobutanoyl)-1,2-0-dioleylglycerol, 3-0-(2-dimethylaminoethyl)carbamoyl-1,2-0-dioleylglycerol, 3-0-(2-diethylaminoethyl)-carbamoyl-1,2-0-dioleylglycerol or 2-0-(2-diethyl-aminoethyl)carbamoyl-1,3-0-dioleylglycerol, and poly(adenylic acid-uridylic acid).
Inventors:
YANO JUNICHI (JP)
OHGI TADAAKI (JP)
OHGI TADAAKI (JP)
Application Number:
PCT/JP1994/000238
Publication Date:
September 01, 1994
Filing Date:
February 17, 1994
Export Citation:
Assignee:
NIPPON SHINYAKU CO LTD (JP)
YANO JUNICHI (JP)
OHGI TADAAKI (JP)
YANO JUNICHI (JP)
OHGI TADAAKI (JP)
International Classes:
A61K31/70; A61K9/127; A61K9/52; A61K9/66; A61K47/10; A61K47/24; A61K47/44; C07C229/06; C07C229/12; C07C237/08; C07C271/16; C07C271/20; C07C279/04; C07C279/20; C07C307/02; C07C333/04; C07D207/08; C07D211/08; C07D241/04; C07D265/30; C07D295/13; C07F9/40; (IPC1-7): A61K31/70; A61K47/24; A61K47/44
Foreign References:
| JPH04352724A | 1992-12-07 | |||
| JPH04210921A | 1992-08-03 | |||
| JPH03240795A | 1991-10-28 | |||
| JPH02191213A | 1990-07-27 | |||
| JPH02295A | 1990-01-05 | |||
| JPS63301825A | 1988-12-08 | |||
| JPS61103824A | 1986-05-22 | |||
| JPS5933222A | 1984-02-23 |
Other References:
See also references of EP 0685234A4
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