Title:
DRUG-CONTAINING OPHTHALMIC LENS
Document Type and Number:
WIPO Patent Application WO/2021/020512
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a drug-containing ophthalmic lens that is superior regarding the amount of a drug incorporated into the lens, the release action of the drug, and the transparency of the lens. An ophthalmic lens material for sustained drug release containing a polymer obtained through copolymerization of a reaction mixture containing a monopolydimethylsiloxane compound represented by general formula (1), N,N-dimethyl acrylamide, 2-hydroxyethyl methacrylate, polyvinyl pyrrolidone, and a crosslinking agent. (In formula (1), X represents a vinyl group, an acryloyloxy group, a methacryloyloxy group, an acryloylamino group, or a methacryloylamino group, Y represents a bond, ꟷR1ꟷ, ꟷR1ꟷR2ꟷ, ꟷR1ꟷR2ꟷR3ꟷ, ꟷR1ꟷR2ꟷR3ꟷR4ꟷ, or ꟷR1ꟷR2ꟷR3ꟷR4ꟷR5ꟷ, wherein R1, R3, and R5 each represent a C1-C3 alkylene group optionally having a substituent, R2 and R4 each represent an oxygen atom, ꟷNHꟷC(O)Oꟷ, ꟷNHꟷC(O)NHꟷ, ꟷOꟷC(O)Oꟷ, or ꟷOꟷC(O)NHꟷ, Z represents a C1-C6 alkyl group, a C3-C6 cyclic alkyl group, or an aryl group, and n represents an integer of 1-1500.)
Inventors:
OSHITA TAKAHIDE (JP)
SUZUKI HIRONORI (JP)
SUZUKI HIRONORI (JP)
Application Number:
PCT/JP2020/029247
Publication Date:
February 04, 2021
Filing Date:
July 30, 2020
Export Citation:
Assignee:
KOWA CO (JP)
International Classes:
G02C7/04; C08F220/28; C08F220/54; C08F230/08
Foreign References:
| JP2009204770A | 2009-09-10 | |||
| JP2020510718A | 2020-04-09 |
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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