Title:
DRUG DISCOVERY METHODS
Document Type and Number:
WIPO Patent Application WO2003067504
Kind Code:
A3
Abstract:
Methods for identifying disease-related pathways that can used to identify drug discovery targets, to identify new uses for known drugs, to identify markers for drug response, and related purposes.
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Inventors:
CHEN RICHARD O (US)
CHO RAYMOND J (US)
FELCIANO RAMON M (US)
HOLLEY BRET (US)
PATEL VIRESH (US)
RICHARDS DANIEL R (US)
SELVARAJAN SUSHMA (US)
STEWARD KEITH (US)
SCHNEIDER SARA TANENBAUM (US)
CHO RAYMOND J (US)
FELCIANO RAMON M (US)
HOLLEY BRET (US)
PATEL VIRESH (US)
RICHARDS DANIEL R (US)
SELVARAJAN SUSHMA (US)
STEWARD KEITH (US)
SCHNEIDER SARA TANENBAUM (US)
Application Number:
PCT/US2003/003006
Publication Date:
September 30, 2004
Filing Date:
February 03, 2003
Export Citation:
Assignee:
INGENUITY SYSTEMS INC (US)
CHEN RICHARD O (US)
CHO RAYMOND J (US)
FELCIANO RAMON M (US)
HOLLEY BRET (US)
PATEL VIRESH (US)
RICHARDS DANIEL R (US)
SELVARAJAN SUSHMA (US)
STEWARD KEITH (US)
SCHNEIDER SARA TANENBAUM (US)
CHEN RICHARD O (US)
CHO RAYMOND J (US)
FELCIANO RAMON M (US)
HOLLEY BRET (US)
PATEL VIRESH (US)
RICHARDS DANIEL R (US)
SELVARAJAN SUSHMA (US)
STEWARD KEITH (US)
SCHNEIDER SARA TANENBAUM (US)
International Classes:
G16B20/00; G16B5/00; G16B5/20; G16B25/10; G16B40/00; G16B45/00; G16B50/00; G16B50/10; (IPC1-7): G06F19/00
Domestic Patent References:
| WO2001055911A1 | 2001-08-02 |
Foreign References:
| EP1158447A1 | 2001-11-28 |
Other References:
VAN HELDEN J ET AL: "Representing and analysing molecular and cellular function using the computer.", BIOLOGICAL CHEMISTRY. 2000 SEP-OCT, vol. 381, no. 9-10, September 2000 (2000-09-01), pages 921 - 935, XP008032491, ISSN: 1431-6730
OLIVER DIANE E ET AL: "Ontology development for a pharmacogenetics knowledge base.", PACIFIC SYMPOSIUM ON BIOCOMPUTING. PACIFIC SYMPOSIUM ON BIOCOMPUTING. 2002, 3 January 2002 (2002-01-03), pages 65 - 76, XP002287419, Retrieved from the Internet [retrieved on 20040629]
KARP P D ET AL: "Integrated pathway-genome databases and their role in drug discovery.", TRENDS IN BIOTECHNOLOGY. JUL 1999, vol. 17, no. 7, July 1999 (1999-07-01), pages 275 - 281, XP004169726, ISSN: 0167-7799
RZHETSKY A ET AL: "Poster: A knowledge model for analysis and simulation of regulatory networks in bioinformatics studies aiming at disease gene discovery", AMIA 99 FALL ANNUAL SYMPOSIUM, 1999, pages 1 - 5, XP002287421, Retrieved from the Internet [retrieved on 20040630]
GOBLE C A ET AL: "TRANSPARENT ACCESS TO MULTIPLE BIOINFORMATICS INFORMATION SOURCES", IBM SYSTEMS JOURNAL, IBM CORP. ARMONK, NEW YORK, US, vol. 40, no. 2, 2001, pages 532 - 551, XP001116348, ISSN: 0018-8670
OLIVER DIANE E ET AL: "Ontology development for a pharmacogenetics knowledge base.", PACIFIC SYMPOSIUM ON BIOCOMPUTING. PACIFIC SYMPOSIUM ON BIOCOMPUTING. 2002, 3 January 2002 (2002-01-03), pages 65 - 76, XP002287419, Retrieved from the Internet
KARP P D ET AL: "Integrated pathway-genome databases and their role in drug discovery.", TRENDS IN BIOTECHNOLOGY. JUL 1999, vol. 17, no. 7, July 1999 (1999-07-01), pages 275 - 281, XP004169726, ISSN: 0167-7799
RZHETSKY A ET AL: "Poster: A knowledge model for analysis and simulation of regulatory networks in bioinformatics studies aiming at disease gene discovery", AMIA 99 FALL ANNUAL SYMPOSIUM, 1999, pages 1 - 5, XP002287421, Retrieved from the Internet
GOBLE C A ET AL: "TRANSPARENT ACCESS TO MULTIPLE BIOINFORMATICS INFORMATION SOURCES", IBM SYSTEMS JOURNAL, IBM CORP. ARMONK, NEW YORK, US, vol. 40, no. 2, 2001, pages 532 - 551, XP001116348, ISSN: 0018-8670
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