DRUG ELUTING STENT AND METHOD OF USE OF THE SAME FOR ENABLING RESTORATION OF FUNCTIONAL ENDOTHELIAL CELL LAYERS

Title:

DRUG ELUTING STENT AND METHOD OF USE OF THE SAME FOR ENABLING RESTORATION OF FUNCTIONAL ENDOTHELIAL CELL LAYERS

Document Type and Number:

WIPO Patent Application WO/2018/113416

Kind Code:

A1

Abstract:

Drug eluting stents，methods of making， using， and verifying long-term stability of the drug eluting stents，and methods for predicting long term stent efficacy and patient safety after implantation of a drug eluting stent are disclosured．In one embodiment，a drug eluting stent may include a stent framework；a drug-containing layer；a drug embedded in the drug-containing layer；and a biocompatible base layer disposed over the stent framework and supporting the drug-containing layer．The drug－containing layer may have an uneven coating thickness．In addition or in alternative，the drug-containing layer may be configured to significantly dissolve／dissipate／disappear between 45 days and 60 days after stent implantation．Stents may reduce，minimize，or eliminate patient risks associated with the implantation of a stent，including，for example，restenosis，thrombosis，and／or MACE．

Inventors:

SUN JIANHUA (US)
BUREAU CHRISTOPHE (CN)
CAI WENBIN (CN)
LI TIANZHU (US)
KANG XIAORAN (CN)

Application Number:

PCT/CN2017/108374

Publication Date:

June 28, 2018

Filing Date:

October 30, 2017

Export Citation:

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Assignee:

SINO MEDICAL SCIENCES TECH INC (CN)

International Classes:

A61F2/00; A61K31/436; B05D3/10

Foreign References:

US20110086081A1	2011-04-14
US20040243097A1	2004-12-02
US20050055078A1	2005-03-10
CN1964749A	2007-05-16

Other References: