Title:
DRUG-LOADED MEDICAL DEVICE AND PREPARATION METHOD, DRUG BALLOON, AND DRUG COATING PREPARATION METHOD
Document Type and Number:
WIPO Patent Application WO/2021/254507
Kind Code:
A1
Abstract:
The present invention relates to a drug-loaded medical device and a preparation method therefor, a drug balloon and a preparation method for a drug coating. The surface of the medical device or the drug balloon has a drug coating. The drug coating comprises a stabilizer and a drug. The stabilizer comprises a triblock amphiphilic polymer with hydrophilic segments at both ends, and the drug coating forms a suspension of nano-drug particles in a water-soluble environment. In this way, the prepared the prepared nano-drug coating is high in drug loading capacity and good in drug delivery effect, and particularly, after the nano-drug coating is in contact with water, the drug can be restored to the original nanoscale, the particle size is hardly increased, the embolism risk caused by particles is avoided, the safety of the device is improved, the drug intake is increased, and the therapeutic effect is improved.
Inventors:
LI MENG (CN)
WANG YUFU (CN)
LI JUNFEI (CN)
HU YAN (CN)
WANG YUFU (CN)
LI JUNFEI (CN)
HU YAN (CN)
Application Number:
PCT/CN2021/101090
Publication Date:
December 23, 2021
Filing Date:
June 18, 2021
Export Citation:
Assignee:
SHANGHAI MICROPORT MEDICAL GROUP CO LTD (CN)
International Classes:
A61M31/00; A61L29/14; A61M25/10
Domestic Patent References:
| WO2014011805A1 | 2014-01-16 |
Foreign References:
| CN111672018A | 2020-09-18 | |||
| CN102883753A | 2013-01-16 | |||
| CN110496251A | 2019-11-26 | |||
| US9242005B1 | 2016-01-26 | |||
| CN110575607A | 2019-12-17 |
Attorney, Agent or Firm:
SHANGHAI SAVVY IP AGENCY CO., LTD. (CN)
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