Title:
DRUG FOR TREATING AFTEREFFECTS OF NOVEL CORONAVIRUS INFECTION
Document Type and Number:
WIPO Patent Application WO/2023/135978
Kind Code:
A1
Abstract:
Provided is a drug for treating aftereffects of a novel coronavirus infection. The drug for treating aftereffects of the novel coronavirus infection contains an acetylcholine receptor agonist as an active ingredient.
Inventors:
KONDO KAZUHIRO (JP)
OKA NAOMI (JP)
OKA NAOMI (JP)
Application Number:
PCT/JP2022/044828
Publication Date:
July 20, 2023
Filing Date:
December 06, 2022
Export Citation:
Assignee:
THE JIKEI UNIV (JP)
International Classes:
A01K67/027; A61K45/00; A61K31/445; A61P3/00; A61P11/02; A61P25/24; A61P25/28; A61P31/14; A61P43/00; C12N15/50; C12N15/85; C12Q1/68; C12Q1/70
Foreign References:
| US20220370382A1 | 2022-11-24 |
Other References:
CROOK, H. ET AL.: "Long covid-mechanisms, risk factors, and management", BMJ, 26 July 2021 (2021-07-26), pages 1648, XP009547307
BORNSTEIN STEFAN R.; VOIT-BAK KARIN; DONATE TIMO; RODIONOV ROMAN N.; GAINETDINOV RAUL R.; TSELMIN SERGEY; KANCZKOWSKI WALDEMAR; MÜ: "Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis?", MOLECULAR PSYCHIATRY, NATURE PUBLISHING GROUP UK, LONDON, vol. 27, no. 1, 17 June 2021 (2021-06-17), London, pages 34 - 37, XP037769088, ISSN: 1359-4184, DOI: 10.1038/s41380-021-01148-4
BRICHER CHOQUE PAMELA NITHZI, VIEIRA RODOLFO P., ULLOA LUIS, GRABULOSA CAREN, IRIGOYEN MARIA CLAUDIA, DE ANGELIS KATIA, LIGEIRO DE: "The Cholinergic Drug Pyridostigmine Alleviates Inflammation During LPS-Induced Acute Respiratory Distress Syndrome", FRONTIERS IN PHARMACOLOGY, vol. 12, XP055873296, DOI: 10.3389/fphar.2021.624895
ALEXANDRIS NIKOLAOS, LAGOUMINTZIS GEORGE, CHASAPIS CHRISTOS T., LEONIDAS DEMETRES D., PAPADOPOULOS GEORGIOS E., TZARTOS SOCRATES J: "Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions", TOXICOLOGY REPORTS, vol. 8, 1 January 2021 (2021-01-01), pages 73 - 83, XP055892376, ISSN: 2214-7500, DOI: 10.1016/j.toxrep.2020.12.013
SIMON J. CLEARY; SIMON C. PITCHFORD; RICHARD T. AMISON; ROBERT CARRINGTON; C. LORENA ROBAINA CABRERA; MÉLIA MAGNEN; MARK R. LOONEY: "Animal models of mechanisms of SARS‐CoV‐2 infection and COVID‐19 pathology", BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, UK, vol. 177, no. 21, 19 July 2020 (2020-07-19), UK , pages 4851 - 4865, XP071172314, ISSN: 0007-1188, DOI: 10.1111/bph.15143
JARNAGIN KURT, ALVAREZ OSCAR, SHRESTA SUJAN, WEBB DAVID R.: "Animal models for SARS-Cov2/Covid19 research-A commentary", BIOCHEMICAL PHARMACOLOGY, ELSEVIER, US, vol. 188, 1 June 2021 (2021-06-01), US , pages 114543, XP093039356, ISSN: 0006-2952, DOI: 10.1016/j.bcp.2021.114543
CALLAWAY EWEN: "The race for coronavirus vaccines: a graphical guide", NATURE, NATURE PUBLISHING GROUP UK, LONDON, vol. 580, no. 7805, 1 April 2020 (2020-04-01), London, pages 576 - 577, XP037104539, ISSN: 0028-0836, DOI: 10.1038/d41586-020-01221-y
BORNSTEIN STEFAN R.; VOIT-BAK KARIN; DONATE TIMO; RODIONOV ROMAN N.; GAINETDINOV RAUL R.; TSELMIN SERGEY; KANCZKOWSKI WALDEMAR; MÜ: "Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis?", MOLECULAR PSYCHIATRY, NATURE PUBLISHING GROUP UK, LONDON, vol. 27, no. 1, 17 June 2021 (2021-06-17), London, pages 34 - 37, XP037769088, ISSN: 1359-4184, DOI: 10.1038/s41380-021-01148-4
BRICHER CHOQUE PAMELA NITHZI, VIEIRA RODOLFO P., ULLOA LUIS, GRABULOSA CAREN, IRIGOYEN MARIA CLAUDIA, DE ANGELIS KATIA, LIGEIRO DE: "The Cholinergic Drug Pyridostigmine Alleviates Inflammation During LPS-Induced Acute Respiratory Distress Syndrome", FRONTIERS IN PHARMACOLOGY, vol. 12, XP055873296, DOI: 10.3389/fphar.2021.624895
ALEXANDRIS NIKOLAOS, LAGOUMINTZIS GEORGE, CHASAPIS CHRISTOS T., LEONIDAS DEMETRES D., PAPADOPOULOS GEORGIOS E., TZARTOS SOCRATES J: "Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions", TOXICOLOGY REPORTS, vol. 8, 1 January 2021 (2021-01-01), pages 73 - 83, XP055892376, ISSN: 2214-7500, DOI: 10.1016/j.toxrep.2020.12.013
SIMON J. CLEARY; SIMON C. PITCHFORD; RICHARD T. AMISON; ROBERT CARRINGTON; C. LORENA ROBAINA CABRERA; MÉLIA MAGNEN; MARK R. LOONEY: "Animal models of mechanisms of SARS‐CoV‐2 infection and COVID‐19 pathology", BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, UK, vol. 177, no. 21, 19 July 2020 (2020-07-19), UK , pages 4851 - 4865, XP071172314, ISSN: 0007-1188, DOI: 10.1111/bph.15143
JARNAGIN KURT, ALVAREZ OSCAR, SHRESTA SUJAN, WEBB DAVID R.: "Animal models for SARS-Cov2/Covid19 research-A commentary", BIOCHEMICAL PHARMACOLOGY, ELSEVIER, US, vol. 188, 1 June 2021 (2021-06-01), US , pages 114543, XP093039356, ISSN: 0006-2952, DOI: 10.1016/j.bcp.2021.114543
CALLAWAY EWEN: "The race for coronavirus vaccines: a graphical guide", NATURE, NATURE PUBLISHING GROUP UK, LONDON, vol. 580, no. 7805, 1 April 2020 (2020-04-01), London, pages 576 - 577, XP037104539, ISSN: 0028-0836, DOI: 10.1038/d41586-020-01221-y
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
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