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Title:
DRUGS FOR IMPROVING OCULAR CIRCULATION DISORDERS
Document Type and Number:
WIPO Patent Application WO/1998/005316
Kind Code:
A1
Abstract:
Drugs for improving ocular circulation disorders which contain as the active ingredient 5-{1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl}-2-methylbenzenesulfonamide or its acid-addition salt. These drugs are usable as preventives or remedies for various diseases caused by ocular circulation disorders, such as glaucoma with normal ocular tension, retinal pigment degeneration, macular degeneration, ischemic optic nerve disease, iridocyclitis, retinal arterial obliteration, retinal venous obliteration, diabetic retinopathy, choroid diseases following retinal lesions, and retinal choroid diseases associated with systemic diseases without showing any side effect. Also when dropped into the eyes, these drugs can exert excellent effects.

Inventors:
OGAWA TAKAHIRO (JP)
WATANABE NORIKO (JP)
WAKI MITSUNORI (JP)
Application Number:
PCT/JP1997/002629
Publication Date:
February 12, 1998
Filing Date:
July 25, 1997
Export Citation:
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Assignee:
SENJU PHARMA CO (JP)
YAMANOUCHI PHARMA CO LTD (JP)
OGAWA TAKAHIRO (JP)
WATANABE NORIKO (JP)
WAKI MITSUNORI (JP)
International Classes:
A61K31/18; (IPC1-7): A61K31/18; A61K9/06; A61K9/08
Domestic Patent References:
WO1993024121A11993-12-09
WO1994001096A11994-01-20
Other References:
ACTA SOCIETATIS OPHTHALMOLOGICAE JAPONICAE, Vol. 100, No. 4, (April 1996), TORU TANIGUCHI et al., "The Influence of Amosulalol Hydrochloride on Rabbit Ocular Tension and Aqueous Humor Kinetics (in Japanese)", pages 279-283; & DATABASE MEDLINE ON STN, US NATIONAL LIBRARY OF MEDICINE, (BETHESDA, MD, USA), No.
See also references of EP 0955045A4
Attorney, Agent or Firm:
Takeuchi, Takashi (Shin-kitahama Building 2-1, Kitahama 3-chome, Chuo-k, Osaka-shi Osaka 541, JP)
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