Title:
Dual alanyl Aminopeptidase and dipeptidyl peptidase IV inhibitors for functionally influencing different cells and for treating immunological, inflammatory, neuronal and other disease
Document Type and Number:
WIPO Patent Application WO2005034940
Kind Code:
A8
Abstract:
The invention relates to substances, which specifically inhibit both Ala-p-nitroanilide-cleaving peptidases as well as Gly-Pro-p-nitroanilide-cleaving peptidases, for use in the field of medicine. The invention also relates to the use of at least one substance of this type or of at least one pharmaceutical or cosmetic composition, which contains at least one of the aforementioned substances, for preventing and treating diseases, particularly for preventing and treating diseases with an overshooting immune response (autoimmune disease, allergies and transplant rejections), other chronic inflammatory diseases, neuronal diseases and cerebral damages, skin diseases (inter alia, acne and psoriasis), tumor diseases and special viral infections (inter alia, SARS).
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Inventors:
ANSORGE SIEGFRIED (DE)
BANK UTE (DE)
NORDHOFF KARSTEN (DE)
TAEGER MICHAEL (DE)
STRIGGOW FRANK (DE)
BANK UTE (DE)
NORDHOFF KARSTEN (DE)
TAEGER MICHAEL (DE)
STRIGGOW FRANK (DE)
Application Number:
PCT/EP2004/011644
Publication Date:
June 01, 2006
Filing Date:
October 15, 2004
Export Citation:
Assignee:
IMTM GMBH (DE)
KEYNEUROTEK AG (DE)
ANSORGE SIEGFRIED (DE)
BANK UTE (DE)
NORDHOFF KARSTEN (DE)
TAEGER MICHAEL (DE)
STRIGGOW FRANK (DE)
KEYNEUROTEK AG (DE)
ANSORGE SIEGFRIED (DE)
BANK UTE (DE)
NORDHOFF KARSTEN (DE)
TAEGER MICHAEL (DE)
STRIGGOW FRANK (DE)
International Classes:
A61K31/404; A61K31/4045; C07C233/83; C07C243/28; C07C251/86; C07C327/48; C07D207/327; C07D295/15; C07D307/52; C07D317/58; C07D403/06; C07D405/06; C07D513/04
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