Title:
DYRK1 INHIBITOR PYRROLO[3,2-C]PYRIDINE DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/277331
Kind Code:
A1
Abstract:
The present invention relates to: a pyrrolo[3,2-c]pyridine derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition containing same as an active ingredient, wherein the pharmaceutical composition is used to prevent or treat diseases associated with dual-specificity tyrosine phosphorylation-regulated kinase 1a (DYRK1A) or dual-specificity tyrosine phosphorylation-regulated kinase 1b (DYRK1B).
Inventors:
LEE HYUK (KR)
KIM KI YOUNG (KR)
LEE GE HYEONG (KR)
PARK A REUM (KR)
KAWK JAE SUNG (KR)
NA YUN JU (KR)
KIM KI YOUNG (KR)
LEE GE HYEONG (KR)
PARK A REUM (KR)
KAWK JAE SUNG (KR)
NA YUN JU (KR)
Application Number:
PCT/KR2022/006446
Publication Date:
January 05, 2023
Filing Date:
May 04, 2022
Export Citation:
Assignee:
KOREA RES INST CHEMICAL TECH (KR)
International Classes:
C07D471/04; A61K31/506; A61P3/10; A61P9/12; A61P25/18; A61P25/28; A61P35/00
Domestic Patent References:
| WO2012098068A1 | 2012-07-26 |
Foreign References:
| US20180179199A1 | 2018-06-28 | |||
| US20140357616A1 | 2014-12-04 | |||
| KR20210058277A | 2021-05-24 |
Other References:
BRYAN MARIAN C.; FALSEY JAMES R.; FROHN MIKE; REICHELT ANDREAS; YAO GUOMIN; BARTBERGER MICHAEL D.; BAILIS JULIE M.; ZALAMEDA LEEAN: "N-substituted azaindoles as potent inhibitors of Cdc7 kinase", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ELSEVIER, AMSTERDAM NL, vol. 23, no. 7, 13 February 2013 (2013-02-13), Amsterdam NL , pages 2056 - 2060, XP028997343, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2013.02.007
Attorney, Agent or Firm:
CHOI, Eun Sun (KR)
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