Title:
ECM CYCLE NORMALIZER
Document Type and Number:
WIPO Patent Application WO/2020/080316
Kind Code:
A1
Abstract:
[Problem] The purpose of the present invention is to provide a novel ECM cycle normalizer. [Solution] The technical features of the present invention for solving the above problem are as follows. 1. A normalizer of the collagen production and uptake cycle in skin fibroblasts, the normalizer having lycoperoside A as an active ingredient. 2. A normalizer of the elastin production and uptake cycle in skin fibroblasts, the normalizer having lycoperoside A as an active ingredient. 3. A normalizer of the ECM cycle in skin fibroblasts, the normalizer having lycoperoside A as an active ingredient.
Inventors:
TAKEDA SHOGO (JP)
YAMADA WAKANA (JP)
SHIMODA HIROSHI (JP)
MURAI HIROMICHI (JP)
YAMADA WAKANA (JP)
SHIMODA HIROSHI (JP)
MURAI HIROMICHI (JP)
Application Number:
PCT/JP2019/040344
Publication Date:
April 23, 2020
Filing Date:
October 13, 2019
Export Citation:
Assignee:
ORYZA OIL & FAT CHEMICAL CO LTD (JP)
International Classes:
C12N15/09; A23K10/30; A61K8/63; A61K31/704; A61K36/81; A61P17/00; A61P43/00; A61Q19/00; C12N5/071; A23L33/105
Domestic Patent References:
| WO2016084886A1 | 2016-06-02 |
Foreign References:
| JP2003532680A | 2003-11-05 | |||
| JP2016063795A | 2016-04-28 | |||
| JP2008530076A | 2008-08-07 |
Other References:
"Oryza Oil & Fat Keeps Skin State Normal with Tomato Seed Extract for Health Food/Cosmetics", THE CHEMICAL DAILY, 1 October 2018 (2018-10-01), pages 5, [retrieved on 20191120]
ORYZA OIL ET AL.: "Tomato Seed Extract", BEAUTY MATERIAL: ANNOUNCED AT HI JAPAN , OCTOBER 3 . FOOD PROCESSING AND INGREDIENTS, 20 November 2019 (2019-11-20), Retrieved from the Internet
TAKEDA, SHOGO ET AL.: "Effect of tomato seed extract and its major saponins on extra cellular matrix in skin", FRAGRANCE JOURNAL, vol. 47, no. 1, 15 January 2019 (2019-01-15), pages 56 - 62
TAKEDA, SHOGO ET AL.: "Effect of tomato seed extract and its major saponins on extra cellular matrix in skin", ABSTRACTS OF 2019 ANNUAL MEETING OF THE JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, March 2019 (2019-03-01)
COSTA, A. ET AL.: "Daily ingestion of nutraceutical-containing proteins, marine polysaccharides, grape and tomato seed extracts, vitamin C, and zinc for the treatment of skin aging and aesthetic quality in men", JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, vol. 66, no. 4, 2012
MINABE, H. ET AL.: "Efficient Improved Extraction of Tomato Saponin Using Shock Waves", CHEM. PHARM. BULL., vol. 59, no. 11, 2011, pages 1406 - 1408, XP055702233
YAHARA, S. ET AL.: "Lycoperosides A - C, three stereoisomeric 23-acetoxyspirosolan-3 a-ol a- lycotetraosides from Lycopersicon esculentum", PHYTOCHEMISTRY, vol. 42, no. 1, 1996, pages 169 - 172, XP055702229
ORYZA OIL ET AL.: "Tomato Seed Extract", BEAUTY MATERIAL: ANNOUNCED AT HI JAPAN , OCTOBER 3 . FOOD PROCESSING AND INGREDIENTS, 20 November 2019 (2019-11-20), Retrieved from the Internet
TAKEDA, SHOGO ET AL.: "Effect of tomato seed extract and its major saponins on extra cellular matrix in skin", FRAGRANCE JOURNAL, vol. 47, no. 1, 15 January 2019 (2019-01-15), pages 56 - 62
TAKEDA, SHOGO ET AL.: "Effect of tomato seed extract and its major saponins on extra cellular matrix in skin", ABSTRACTS OF 2019 ANNUAL MEETING OF THE JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, March 2019 (2019-03-01)
COSTA, A. ET AL.: "Daily ingestion of nutraceutical-containing proteins, marine polysaccharides, grape and tomato seed extracts, vitamin C, and zinc for the treatment of skin aging and aesthetic quality in men", JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, vol. 66, no. 4, 2012
MINABE, H. ET AL.: "Efficient Improved Extraction of Tomato Saponin Using Shock Waves", CHEM. PHARM. BULL., vol. 59, no. 11, 2011, pages 1406 - 1408, XP055702233
YAHARA, S. ET AL.: "Lycoperosides A - C, three stereoisomeric 23-acetoxyspirosolan-3 a-ol a- lycotetraosides from Lycopersicon esculentum", PHYTOCHEMISTRY, vol. 42, no. 1, 1996, pages 169 - 172, XP055702229
Attorney, Agent or Firm:
KUMAZAKI Yoichi (JP)
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