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Title:
EDARAVONE PHARMACEUTICAL COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2019/205700
Kind Code:
A1
Abstract:
Disclosed in the present invention are an edaravone pharmaceutical composition and an application thereof as a sublingual preparation, the pharmaceutical composition containing edaravone or a salt thereof and mannitol. A sublingual administration preparation can avoid the first-pass effect of the liver, and samples feature good stability, convenience of transport and of use, among other advantages.

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Inventors:
WANG YILONG (CN)
WANG YONGJUN (CN)
ZHAO XINGQUAN (CN)
ZHANG ANYUAN (CN)
Application Number:
PCT/CN2018/124247
Publication Date:
October 31, 2019
Filing Date:
December 27, 2018
Export Citation:
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Assignee:
BEIJING TIANTAN HOSPITAL CAPITAL MEDICAL UNIV (CN)
NANJING BAIXINYU PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K9/00; A61K9/20; A61K31/4152; A61K47/10; A61K47/26; A61K47/38; A61P9/10; A61P21/00; A61P25/00; A61P25/02
Foreign References:
CN107773545A2018-03-09
CN105616405A2016-06-01
CN201810392676A2018-04-27
CN201810797624A2018-07-19
Other References:
YAKUGAKU ZASSHI, vol. 124, no. 3, 2004, pages 99 - 111
See also references of EP 3785698A4
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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