Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
CRISPR/CAS EFFECTOR PROTEIN AND SYSTEM
Document Type and Number:
WIPO Patent Application WO/2019/214604
Kind Code:
A1
Abstract:
The present invention relates to the field of nucleic acid editing, and in particular, to the technical field of clustered regularly interspaced short palindromic repeat (CRISPR). A Cas effector protein, comprising a fusion protein of said protein and nucleic acid molecules encoding same. Provided are a complex and a compound for nucleic acid editing (e.g. gene or genome editing), comprising the Cas effector protein or the fusion protein, or the nucleic acid molecules encoding same. Also provided is a method for nucleic acid editing (e.g. gene or genome editing), which uses the Cas effector protein or the fusion protein.

More Like This:
WO/2024/031188COMPOSITION FOR MODIFYING A T CELL
WO/2002/033109FERMENTATION METHOD FOR PRODUCTION OF HETEROLOGOUS GENE PRODUCTS IN LACTIC ACID BACTERIA
WO/2019/232253GENE EDITING OF MONOGENIC DISORDERS IN HUMAN HEMATOPOIETIC STEM CELLS -- CORRECTION OF X-LINKED AGAMMAGLOBULINEMIA (XLA)
Inventors:
LAI JINSHENG (CN)
ZHOU YINGSI (CN)
ZHU JINJIE (CN)
ZHANG XIANGBO (CN)
ZHAO HAIMING (CN)
SONG WEIBIN (CN)
Application Number:
PCT/CN2019/085826
Publication Date:
November 14, 2019
Filing Date:
May 07, 2019
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV CHINA AGRICULTURAL (CN)
International Classes:
C12N9/22; C12N15/113; C12N15/85
Domestic Patent References:
WO2018064352A12018-04-05
Foreign References:
CN107784200A2018-03-09
CN105907785A2016-08-31
Other References:
YAN, W. X.: "Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory Protein", MOLECULAR CELL, vol. 70, no. 2, 19 April 2018 (2018-04-19), pages 1 - 19, XP055529724, ISSN: 1097-2765, DOI: 10.1016/j.molcel.2018.02.028
COX, D. B. T.ET AL: "RNA editing with CRISPR-Casl3", SCIENCE, vol. 358, no. 6366, pages 1019 - 1027, XP055491658, ISSN: 0036-8075, DOI: 10.1126/science.aaq0180
MAKAROVA, K. S.: "SnapShot: Class 2 CRISPR-Cas Systems", CELL, vol. 168, no. 1, 12 January 2017 (2017-01-12), pages 1 - 2, XP029882153, ISSN: 0092-8674, DOI: 10.1016/j.cell.2016.12.038
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: AEROSOL GENERATING PRODUCT AND SYSTEM

Next Patent: WATER SOURCE HEAT PUMP