Title:
EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/033410
Kind Code:
A1
Abstract:
An EGFR inhibitor having the structure of formula (I), a preparation method therefor, a pharmaceutical composition containing same, a use of same as an EGFR inhibitor, and a use of same in preparing a drug for treating and/or preventing a cancer, a tumor, or a metastatic disease at least partially related to an EGFR exon 20 insertion, deletion, or other mutation, and in particular a use in preparing a drug for treating and/or preventing a hyperproliferative disease and an induced cell death disorder. Each substituent of formula (I) has the same definition as in the description.
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Inventors:
YANG FEI (CN)
YANG SHUQUN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
YANG SHUQUN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
Application Number:
PCT/CN2021/111411
Publication Date:
February 17, 2022
Filing Date:
August 09, 2021
Export Citation:
Assignee:
ABBISKO THERAPEUTICS CO LTD (CN)
International Classes:
C07D239/94; A61K31/517; A61P35/00; C07D401/06; C07D401/10; C07D401/12; C07D401/14; C07D403/06; C07D403/10; C07D403/12; C07D403/14
Domestic Patent References:
| WO2021030711A1 | 2021-02-18 | |||
| WO2007082434A1 | 2007-07-26 | |||
| WO2020009156A1 | 2020-01-09 | |||
| WO2020068867A1 | 2020-04-02 |
Foreign References:
| CN101304978A | 2008-11-12 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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