Title:
EGFR INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2019/218987
Kind Code:
A1
Abstract:
Provided herein are compounds, salts, solid forms, and pharmaceutical compositions that are related to EGFR inhibitors, such as N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide, as well as methods of preparing the same. Also provided herein are methods of using the compounds, salts, solid forms, and pharmaceutical compositions for the treatment of diseases or disorders, such as cancer.
Inventors:
DAI XING (CN)
JIANG YUEHENG (CN)
JIANG YUEHENG (CN)
Application Number:
PCT/CN2019/086748
Publication Date:
November 21, 2019
Filing Date:
May 14, 2019
Export Citation:
Assignee:
INVENTISBIO SHANGHAI LTD (CN)
International Classes:
C07D403/04; A61K31/506; A61P35/00
Foreign References:
| CN106478605A | 2017-03-08 | |||
| CN106478605A | 2017-03-08 | |||
| CN105085489A | 2015-11-25 | |||
| CN105085489A | 2015-11-25 | |||
| CN103702990A | 2014-04-02 | |||
| CN107522690A | 2017-12-29 | |||
| CN106699736A | 2017-05-24 |
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (CN)
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