ELECTRONIC LABEL-FREE DNA AND GENOME SEQUENCING

Title:

ELECTRONIC LABEL-FREE DNA AND GENOME SEQUENCING

Document Type and Number:

WIPO Patent Application WO/2017/139493

Kind Code:

A3

Abstract:

A method of manufacturing a device useable in DNA or genome sequencing comprises disposing pairs of electrodes on a substrate, the electrodes within each pair separated by a nanogap; depositing a resist layer over the electrodes; patterning the resist layer to create an exposed region on each electrode at or near each nanogap; roughening the electrode surface within each exposed region using various methods; and exposing the exposed regions to biomolecules, wherein one biomolecule bridges each nanogap of each electrode pair, with each end of each biomolecule bound to the electrodes at each exposed region.

Inventors:

CHOI CHULMIN (US)
JIN SUNGHO (US)
MOLA PAUL W (US)
MERRIMAN BARRY L (US)

Application Number:

PCT/US2017/017231

Publication Date:

September 14, 2017

Filing Date:

February 09, 2017

Export Citation:

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Assignee:

ROSWELL BIOTECHNOLOGIES INC (US)

International Classes:

H01L35/34

Foreign References:

US5486449A	1996-01-23
US20090027036A1	2009-01-29
US6464889B1	2002-10-15
US20100288543A1	2010-11-18
US20130245416A1	2013-09-19
US20130108956A1	2013-05-02
US20110091787A1	2011-04-21
US20140170567A1	2014-06-19
US8652768B1	2014-02-18

Other References: