Title:
Β-ELEMENE 14-POSITION DERIVATIVE AND APPLICATION OF SAME IN THE TREATMENT OF ATHEROSCLEROSIS
Document Type and Number:
WIPO Patent Application WO/2016/015480
Kind Code:
A1
Abstract:
The present invention relates to the fields of organic synthesis and pharmaceutical chemistry, and specifically relates to a β-elemene 14-position derivative (I) or (II), wherein R1 and R2 are defined in the description. Also disclosed in the present invention are a method for preparing said β-elemene 14-position derivatives and the anti-atherosclerotic application of same.
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Inventors:
SHANG JING (CN)
XU JINYI (CN)
XU HAI (CN)
XU TING (CN)
WANG RUOYAN (CN)
DUAN WENLI (CN)
CHEN JICHAO (CN)
BAI RENREN (CN)
XU JINYI (CN)
XU HAI (CN)
XU TING (CN)
WANG RUOYAN (CN)
DUAN WENLI (CN)
CHEN JICHAO (CN)
BAI RENREN (CN)
Application Number:
PCT/CN2015/075326
Publication Date:
February 04, 2016
Filing Date:
March 27, 2015
Export Citation:
Assignee:
DALIAN YUANDA PHARMACEUTICAL TECHNOLOGY DEV CO LTD (CN)
International Classes:
C07C67/08; A61K31/216; A61K31/22; A61K31/225; A61K31/235; A61K31/24; A61K31/341; A61K31/4406; A61K31/4409; A61P9/10; C07C69/145; C07C69/24; C07C69/40; C07C69/42; C07C69/587; C07C69/618; C07C69/65; C07C69/78; C07C69/83; C07C69/84; C07C69/92; C07D213/79; C07D213/80; C07D213/803; C07D307/68
Foreign References:
| CN104119221A | 2014-10-29 | |||
| CN1844084A | 2006-10-11 | |||
| US20100120907A1 | 2010-05-13 |
Other References:
JICHAO CHEN ET AL.: "Design, synthesis and antioxidant activity evaluation of novel beta-elemene derivatives", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 24, 2 June 2014 (2014-06-02), pages 3407 - 3411, XP028864125, DOI: doi:10.1016/j.bmcl.2014.05.078
Attorney, Agent or Firm:
NANJING JINGWEI PATENT & TRADEMARK AGENCY CO., LTD. (CN)
南京经纬专利商标代理有限公司 (CN)
南京经纬专利商标代理有限公司 (CN)
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