EMULSION FORMULATION ADJUVANT COMPOSITION AND PREPARATION METHOD THEREFOR

Title:

EMULSION FORMULATION ADJUVANT COMPOSITION AND PREPARATION METHOD THEREFOR

Document Type and Number:

WIPO Patent Application WO/2024/053934

Kind Code:

A1

Abstract:

The present invention relates to emulsion formulation adjuvant composition and a preparation method therefor. The emulsion formulation adjuvant composition of the present invention is prepared by adding TLR2 and/or TLR3, TLR7, TLR9 ligands or lipids to an O/W-type emulsion-based formulation containing squalene, alpha-tocopherol, and surfactants having proven safety and efficacy, and the ratio of components of each composition is optimized to significantly increase humoral and cellular immune responses, and thus the present invention can be effectively used to prepare various vaccines for viruses including respiratory viruses and the like.

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Inventors:

YUM JUNG SUN (KR)
AHN BYUNG CHEOL (KR)
JUNG EUNJUNG (KR)

Application Number:

PCT/KR2023/013016

Publication Date:

March 14, 2024

Filing Date:

August 31, 2023

Export Citation:

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Assignee:

CHA VACCINE RES INSTITUTE CO LTD (KR)

International Classes:

A61K39/39; A61K39/00

Domestic Patent References:

WO2018232257A1

2018-12-20

Foreign References:

KR20100009576A	2010-01-27
KR102098097B1	2020-05-26
KR20090066323A	2009-06-23
KR100592825B1	2006-06-23

Attorney, Agent or Firm:

LEE, Won Hee (KR)

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