Title:
ENANTIOMER ANALYSIS METHOD
Document Type and Number:
WIPO Patent Application WO/2017/057433
Kind Code:
A1
Abstract:
The present invention addresses the problem of developing a novel methodology that provides superior analysis of enantiomers. This problem is solved by means of an enantiomer analysis method comprising (1) to (3) as follows. (1) A mixture of a first compound and second compound forming a pair of enantiomers is reacted with an axially chiral compound that is one of a pair of axially chiral isomers to generate a derivative mixture that includes a first derivative obtained from the reaction of the first compound with the axially chiral compound and a second derivative obtained from the reaction of the second compound with the axially chiral compound; (2) the first derivative and the second derivative are separated in the derivative mixture; and (3) the separated first derivative and second derivative are detected by mass spectrometry.
Inventors:
HARADA MASASHI (JP)
KARAKAWA SACHISE (JP)
SHIMBO KAZUTAKA (JP)
YAMADA NAOYUKI (JP)
KARAKAWA SACHISE (JP)
SHIMBO KAZUTAKA (JP)
YAMADA NAOYUKI (JP)
Application Number:
PCT/JP2016/078576
Publication Date:
April 06, 2017
Filing Date:
September 28, 2016
Export Citation:
Assignee:
AJINOMOTO KK (JP)
International Classes:
G01N30/88; B01D15/38; C07C233/62; C07C271/58; C07D207/46; C07D213/40; C07D401/12; G01N27/62; G01N30/06
Foreign References:
| JP2014034573A | 2014-02-24 | |||
| JP2012521415A | 2012-09-13 | |||
| JPH07128319A | 1995-05-19 |
Other References:
TETSUTARO HATTORI ET AL.: "Application of Axially Dissymmetric 1,1'-Binaphthyl Derivatives to Chiral Derivatizing Agents", JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN, vol. 50, no. 11, 1992, pages 986 - 996, XP055371666
See also references of EP 3358346A4
See also references of EP 3358346A4
Attorney, Agent or Firm:
SAKAI INTERNATIONAL PATENT OFFICE (JP)
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