Title:
ENANTIOSELECTIVE AMINATION AND ETHERIFICATION
Document Type and Number:
WIPO Patent Application WO2004024684
Kind Code:
A3
Abstract:
The present invention is directed to a catalyst composition, comprising: (1) a catalyst precursor having the general structure MSXn wherein M is a transition metal selected from the group consisting of iridium, molybdenum, and tungsten; S is a coordinating ligand; X is a counterion; and n is an integer from 0 to 5; and (2) a phosphoramidite ligand having the structure wherein O-Cn-O is an aliphatic or aromatic diolate and wherein R1,< >R2, R3 and R4 are selected from the group consisting of substituted or unsubstituted aryl groups, substituted or unsubstituted heteroaryl groups, substituted or unsubstituted aliphatic groups, and combinations thereof, with the proviso that at least one of R1, R2, R3, or R4 must be a substituted or unsubstituted aryl or heteroaryl group. The present invention is also directed to activated catalysts made from the above catalyst composition, as well as methods of allylic amination and etherification using the above catalysts.
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Inventors:
HARTWIG JOHN F (US)
SHU CHUTIAN (US)
OHMURA TOSHIMICHI (JP)
KIENER CHRISTOPH (DE)
LOPEZ FERNANDO GARCIA (ES)
SHU CHUTIAN (US)
OHMURA TOSHIMICHI (JP)
KIENER CHRISTOPH (DE)
LOPEZ FERNANDO GARCIA (ES)
Application Number:
PCT/US2003/028718
Publication Date:
May 13, 2004
Filing Date:
September 12, 2003
Export Citation:
Assignee:
UNIV YALE (US)
HARTWIG JOHN F (US)
SHU CHUTIAN (US)
OHMURA TOSHIMICHI (JP)
KIENER CHRISTOPH (DE)
LOPEZ FERNANDO GARCIA (ES)
HARTWIG JOHN F (US)
SHU CHUTIAN (US)
OHMURA TOSHIMICHI (JP)
KIENER CHRISTOPH (DE)
LOPEZ FERNANDO GARCIA (ES)
International Classes:
B01J31/18; C07B53/00; C07C209/16; C07F9/6571; (IPC1-7): B01J31/00
Foreign References:
| US5089460A | 1992-02-18 | |||
| US5166281A | 1992-11-24 | |||
| US5395971A | 1995-03-07 | |||
| US5962360A | 1999-10-05 | |||
| US4859799A | 1989-08-22 | |||
| US20030199713A1 | 2003-10-23 |
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