ENDOTHELIAL CELL SPECIFICALLY BINDING PEPTIDES

Title:

ENDOTHELIAL CELL SPECIFICALLY BINDING PEPTIDES

Document Type and Number:

WIPO Patent Application WO2004056080

Kind Code:

A9

Abstract:

The present invention relates to peptides that specifically bind to endothelial cells. The peptides can be incorporated into gene delivery vector particles and can also direct therapeutic agents, including proteins such as growth factors and cytokines as well as small molecules. The vector particles, peptides, or small molecules can be used for the treatment of cancer and cardiovascular diseases such as ischemic heart disease, peripheral limb disease, vein graft stenosis and restenosis.

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Inventors:

LIAU GENE (US)
STEFANSSON STEINGRIMUR (US)
SU JOSEPH (US)

Application Number:

PCT/EP2003/014407

Publication Date:

April 21, 2005

Filing Date:

December 17, 2003

Export Citation:

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Assignee:

NOVARTIS AG (CH)
NOVARTIS PHARMA GMBH (AT)
LIAU GENE (US)
STEFANSSON STEINGRIMUR (US)
SU JOSEPH (US)

International Classes:

C07K7/06; C07K14/005; A61K38/00; A61K48/00; (IPC1-7): C07K14/005; C07K7/06; C07K19/00; C12N15/63; C12N15/62; C12N15/33; A61K38/08; A61K48/00

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