Title:
ENEMA FOR RECTAL APPLICATION
Document Type and Number:
WIPO Patent Application WO/2016/121147
Kind Code:
A1
Abstract:
Provided is an enema for rectal application, which can be used for treating inflammatory bowel disease or preventing the recurrent of inflammatory bowel disease and contains budesonide as an active ingredient. An enema for rectal application, which is characterized by containing budesonide as an active ingredient and being administered in such a manner that a single dose of 1.5 to 2.5 mg of budesonide can be taken twice a day for 6 weeks for treating inflammatory bowel disease or preventing the recurrent of inflammatory bowel disease; an enema for rectal application as mentioned above, wherein the dose of budesonide per one time is 2.0 mg; any one of the above-mentioned enemas for rectal application, which is administered for treating ulcerative colitis or Crohn's disease or preventing the recurrence of ulcerative colitis or Crohn's disease; and any one of the aforementioned enemas for rectal application, which is in the form of a foam or a liquid.
Inventors:
YAMADA YOJI (JP)
KONDO SYOJI (JP)
KAJIOKA TOSHIFUMI (JP)
KONDO SYOJI (JP)
KAJIOKA TOSHIFUMI (JP)
Application Number:
PCT/JP2015/070667
Publication Date:
August 04, 2016
Filing Date:
July 21, 2015
Export Citation:
Assignee:
EA PHARMA CO LTD (JP)
International Classes:
A61K31/58; A61K9/08; A61K9/12; A61P1/04
Foreign References:
| US20140349982A1 | 2014-11-27 |
Other References:
MIKIHIRO FUJIYA ET AL.: "Mucosal healing in ulcerative colitis", THE JAPANESE JOURNAL OF GASTRO-ENTEROLOGY, vol. 110, 2013, pages 1900 - 1908, XP055463943
LINDGREN ET AL.: "Effect of Budesonide Enema on Remission and Relapse Rate in Distal Ulcerative Colitis and Proctitis", SCAND. J. GASTROENTEROL., vol. 37, no. 6, 2002, pages 705 - 710, XP009504405
LINDGREN ET AL.: "Effect of Budesonide Enema on Remission and Relapse Rate in Distal Ulcerative Colitis and Proctitis", SCAND. J. GASTROENTEROL., vol. 37, no. 6, 2002, pages 705 - 710, XP009504405
Attorney, Agent or Firm:
SHIGA Masatake et al. (JP)
Masatake Shiga (JP)
Masatake Shiga (JP)
Download PDF: