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Patent Searching and Data


Title:
ENGINEERED BACTERIAL STRAIN THAT REDUCES ANTIBIOTIC-RESISTANT ENTEROCOCCUS COLONIZATION IN THE GI TRACT
Document Type and Number:
WIPO Patent Application WO/2018/152148
Kind Code:
A8
Abstract:
The present disclosure provides engineered modified strains of enterococcus faecalis (EF) that is able to produce bacteriocin but is inefficient at establishing long-term colonization of the GI track in an animal. Compositions comprising the modified strain and methods of use are also disclosed.

Inventors:
SALZMAN NITA (US)
KRISTICH CHRISTOPHER (US)
KOMMINENI SUSHMA (US)
Application Number:
PCT/US2018/018099
Publication Date:
August 15, 2019
Filing Date:
February 14, 2018
Export Citation:
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Assignee:
MEDICAL COLLEGE WISCONSIN INC (US)
International Classes:
A61K39/085; A61P31/04; C12N1/21; C12N15/31; C12R1/01; C12R1/44; C12R1/46
Attorney, Agent or Firm:
BABEL, Angeline, R. (US)
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