Title:
ENHANCED BRAIN FUNCTION BY GABA-ERGIC STIMULATION
Document Type and Number:
WIPO Patent Application WO2002000221
Kind Code:
B1
Abstract:
Methods are disclosed for improving age-related decreases in cortical function by increasing the activity of inhibitory pathways, such as GABA-ergic pathways, in the central nervous system. In particular examples, subjects with age-related decreases in cortical function are treated by administering therapeutically effective amounts of a GABA-ergic agonist. The disclosed methods also enable screening for drugs that inhibit an age-related decline in cortical function, for example by exposing a subject to a test agent, and measuring an increase in GABA-ergic cortical inhibitory activity.
Inventors:
LEVENTHAL AUDIE G (US)
Application Number:
PCT/US2001/019719
Publication Date:
February 28, 2002
Filing Date:
June 20, 2001
Export Citation:
Assignee:
UNIV UTAH RES FOUND (US)
LEVENTHAL AUDIE G (US)
LEVENTHAL AUDIE G (US)
International Classes:
A61K31/415; A61K31/42; A61K31/52; A61K31/53; (IPC1-7): A61K31/52; A61K31/415; A61K31/42; A61K31/53
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