Title:
ENTERIC FORMULATIONS OF PROANTHOCYANIDIN POLYMER DIETARY SUPPLEMENTS AND METHODS FOR PREPARING SAME
Document Type and Number:
WIPO Patent Application WO2000047062
Kind Code:
A3
Abstract:
The present invention provides for a method for preparing a proanthocyanidin enriched composition useful as a dietary supplement. The proanthocyanidin polymer composition can be synthesized by the method comprising the steps of precipitating Croton ssp latex by adjusting the pH of the latex; removing precipitated residue from the precipitated latex to produce a filtrate; concentrating the filtrate to obtain a retentate; and drying the filtrate, the filtrate being essentially free of anti-foaming agents. A further optional additional step includes removing additional taspine from the retentate by contacting said retentate with chromatographic media. A proanthocyanidin composition product made by this process is also described. Dietary supplements containing a proanthocyanidin polymer enriched composition as well as dietary supplements containing a proanthocyanidin polymer enriched composition and an additional herbal agent, e.g., ginger, cinnamon, and peppermint oil are also described.
Inventors:
SESIN DAVID F (US)
JOLAD SHIVANAND D (US)
SAN-LAUNG CHOW (US)
LEE GEORGE J (US)
CHOW JOHN W S (US)
CARLSON THOMAS J (US)
JOLAD SHIVANAND D (US)
SAN-LAUNG CHOW (US)
LEE GEORGE J (US)
CHOW JOHN W S (US)
CARLSON THOMAS J (US)
Application Number:
PCT/US2000/002687
Publication Date:
December 14, 2000
Filing Date:
February 01, 2000
Export Citation:
Assignee:
SHAMAN PHARMACEUTICALS INC (US)
SESIN DAVID F (US)
JOLAD SHIVANAND D (US)
SAN LAUNG CHOW (US)
LEE GEORGE J (US)
CHOW JOHN W S (US)
CARLSON THOMAS J (US)
SESIN DAVID F (US)
JOLAD SHIVANAND D (US)
SAN LAUNG CHOW (US)
LEE GEORGE J (US)
CHOW JOHN W S (US)
CARLSON THOMAS J (US)
International Classes:
A23L1/30; A61K36/47; A61K36/534; A61K36/54; A61K36/9068; A61K9/20; A61K9/28; (IPC1-7): A61K31/765
Domestic Patent References:
| WO1998016111A1 | 1998-04-23 | |||
| WO1997044407A1 | 1997-11-27 |
Foreign References:
| US5494661A | 1996-02-27 | |||
| US5211944A | 1993-05-18 |
Other References:
DATABASE BIOSIS BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1987, NAMBA T. ET AL.: "Studies on the natural medicinal resources from Sri-Lanka ...", XP002142639
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