Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
ENZYME AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/167250
Kind Code:
A1
Abstract:
Provides an artificial enzyme obtained by improving upon a sequence of a natural nicotine dehydrogenase, wherein the improvement comprises replacing at least one amino acid hindering product release with an amino acid with a smaller side chain, thereby improving a catalytic rate.

Inventors:
XU PING (CN)
TANG HONGZHI (CN)
ZHANG KUNZHI (CN)
WU GENG (CN)
TAO FEI (CN)
Application Number:
PCT/CN2017/078912
Publication Date:
October 05, 2017
Filing Date:
March 31, 2017
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV SHANGHAI JIAOTONG (CN)
International Classes:
C12N9/06; A61K38/44; A61P25/34; C12N15/53
Foreign References:
CN103952429A2014-07-30
CN102796681A2012-11-28
US20160032298A12016-02-04
Other References:
DATABASE Genbank registry [O] 18 June 2014 (2014-06-18), XP055427207, Database accession no. CP006979
DATABASE GENBANK [O] 18 May 2013 (2013-05-18), XP055427213, Database accession no. WP_013973880
REN, YILING ET AL.: "Research Advances on Structural Biology of Nicotine-Degrading Related Enzymes", GUANGZHOU CHEMICAL INDUSTRY, vol. 40, no. 10, 31 May 2012 (2012-05-31), pages 4 - 7, ISSN: 1001-9677
SONG, XUE ET AL.: "A New Strategy for Smoking Cessation: Characterization of a Bacterial Enzyme for the Degradation of Nicotine", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 137, 3 August 2015 (2015-08-03), pages 10136 - 10139, XP055368398, ISSN: 0002-7863
Attorney, Agent or Firm:
SUNRAY INTELLECTUAL PROPERTY ATTORNEYS (CN)
Download PDF: